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Objective. To describe risk factors associated to the incidence of type 2 diabetes (T2D) in Mexican population and to define phenotypic (clinical, anthropometric, metabolic) characteristics present in the individual who will convert to diabetes, regardless of time of onset. Materials and methods. Th...
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| Format: | Article |
| Language: | English |
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Instituto Nacional de Salud Pública
2014-07-01
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| Series: | Salud Pública de México |
| Subjects: | |
| Online Access: | http://www.saludpublica.mx/index.php/spm/article/view/7351 |
| _version_ | 1828740636299231232 |
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| author | Clicerio González-Villalpando Claudio Alberto Dávila-Cervantes Mireya Zamora-Macorra Belem Trejo-Valdivia María Elena González-Villalpando |
| author_facet | Clicerio González-Villalpando Claudio Alberto Dávila-Cervantes Mireya Zamora-Macorra Belem Trejo-Valdivia María Elena González-Villalpando |
| author_sort | Clicerio González-Villalpando |
| collection | DOAJ |
| description | Objective. To describe risk factors associated to the incidence of type 2 diabetes (T2D) in Mexican population and to define phenotypic (clinical, anthropometric, metabolic) characteristics present in the individual who will convert to diabetes, regardless of time of onset. Materials and methods. The Mexico City Diabetes Study began in 1990, with 2 282 participants, and had three subsequent phases: 1994, 1998, and 2008. A systematic evaluation with an oral glucose tolerance test was performed in each phase. For diagnosis of T2D, American Diabetes Association criteria were used. Results. The population at risk was 1939 individuals. Subjects who were in the converter stage (initially non diabetic that eventually converted to T2D) had, at baseline, higher BMI (30 vs 27), systolic blood pressure (119 vs 116 mmHg), fasting glucose (90 vs 82mg/dl), triglycerides (239 vs 196mg/dl), and cholesterol (192 vs 190mg/dl), compared with subjects who remained non converters (p menor que 0.05). Conclusion. The phenotype described represents a potentially identifiable phase and a target for preventive intervention. |
| first_indexed | 2024-04-13T00:43:25Z |
| format | Article |
| id | doaj.art-8e75e50a695c4ef29d9c46a27098b7c5 |
| institution | Directory Open Access Journal |
| issn | 0036-3634 1606-7916 |
| language | English |
| last_indexed | 2024-04-13T00:43:25Z |
| publishDate | 2014-07-01 |
| publisher | Instituto Nacional de Salud Pública |
| record_format | Article |
| series | Salud Pública de México |
| spelling | doaj.art-8e75e50a695c4ef29d9c46a27098b7c52022-12-22T03:10:04ZengInstituto Nacional de Salud PúblicaSalud Pública de México0036-36341606-79162014-07-0156431732210.21149/spm.v56i4.735115810_Clicerio González-Villalpando0Claudio Alberto Dávila-Cervantes1Mireya Zamora-Macorra2Belem Trejo-Valdivia3María Elena González-Villalpando4Unidad de Investigación en Diabetes y Riesgo Cardiovascular, Instituto Nacional de Salud Pública. México; Centro de Estudios en Diabetes. México.Facultad Latinoamericana de Ciencias Sociales. México DF, México.Unidad de Investigación en Diabetes y Riesgo Cardiovascular, Instituto Nacional de Salud Pública. México; Centro de Estudios en Diabetes. México.Dirección de Estadística, Centro de Investigación en Evaluación y Encuestas, Instituto Nacional de Salud Pública. México.Centro de Estudios en Diabetes. México.Objective. To describe risk factors associated to the incidence of type 2 diabetes (T2D) in Mexican population and to define phenotypic (clinical, anthropometric, metabolic) characteristics present in the individual who will convert to diabetes, regardless of time of onset. Materials and methods. The Mexico City Diabetes Study began in 1990, with 2 282 participants, and had three subsequent phases: 1994, 1998, and 2008. A systematic evaluation with an oral glucose tolerance test was performed in each phase. For diagnosis of T2D, American Diabetes Association criteria were used. Results. The population at risk was 1939 individuals. Subjects who were in the converter stage (initially non diabetic that eventually converted to T2D) had, at baseline, higher BMI (30 vs 27), systolic blood pressure (119 vs 116 mmHg), fasting glucose (90 vs 82mg/dl), triglycerides (239 vs 196mg/dl), and cholesterol (192 vs 190mg/dl), compared with subjects who remained non converters (p menor que 0.05). Conclusion. The phenotype described represents a potentially identifiable phase and a target for preventive intervention.http://www.saludpublica.mx/index.php/spm/article/view/7351Diabetes mellitusrisk factorsincidencephenotypeMexico |
| spellingShingle | Clicerio González-Villalpando Claudio Alberto Dávila-Cervantes Mireya Zamora-Macorra Belem Trejo-Valdivia María Elena González-Villalpando _ Salud Pública de México Diabetes mellitus risk factors incidence phenotype Mexico |
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| topic | Diabetes mellitus risk factors incidence phenotype Mexico |
| url | http://www.saludpublica.mx/index.php/spm/article/view/7351 |