Calreticulin expression in human cardiac myocytes induces ER stress‐associated apoptosis

Calreticulin expression in human cardiac myocytes induces ER stress‐associated apoptosis

Abstract The global burden of heart failure following myocardial ischemia‐reperfusion (IR) injury is a growing problem. One pathway that is key to understanding the progression of myocardial infarction and IR injury is the endoplasmic reticulum (ER) stress pathway, which contributes to apoptosis sig...

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Bibliographic Details
Main Authors: Michael W. Stoner, Charles F. McTiernan, Iain Scott, Janet R. Manning
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Physiological Reports
Subjects:
AC16 cells
calreticulin
ER stress
heart
Online Access:https://doi.org/10.14814/phy2.14400

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