Circulating differentiated and senescent lymphocyte subsets and incident diabetes risk in older adults: The Cardiovascular Health Study

Circulating differentiated and senescent lymphocyte subsets and incident diabetes risk in older adults: The Cardiovascular Health Study

Abstract Introduction Cellular senescence is a feature of aging implicated in the pathophysiology of diabetes mellitus (DM). Whether senescent lymphocytes are associated with the future occurrence of DM is uncertain. Methods We used cryopreserved peripheral blood mononuclear cells collected from 186...

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Bibliographic Details
Main Authors: Nels C. Olson, Margaret F. Doyle, Petra Buzkova, Sally A. Huber, Ian H. deBoer, Colleen M. Sitlani, Russell P. Tracy, Bruce M. Psaty, Kenneth J. Mukamal, Joseph A. Delaney
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Endocrinology, Diabetes & Metabolism
Subjects:
cellular senescence
diabetes mellitus
epidemiology
lymphocyte subsets
Online Access:https://doi.org/10.1002/edm2.384

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