The Protective Role of Decorin in Hepatic Metastasis of Colorectal Carcinoma

The Protective Role of Decorin in Hepatic Metastasis of Colorectal Carcinoma

Decorin, the prototype member of the small leucine-rich proteoglycan gene family of extracellular matrix (ECM) proteins, acts as a powerful tumor suppressor by inducing the p21<sup>Waf1/Cip1</sup> cyclin-dependent kinase inhibitor, as well as through its ability to directly bind and bloc...

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Bibliographic Details
Main Authors: Andrea Reszegi, Zsolt Horváth, Katalin Karászi, Eszter Regős, Victoria Postniková, Péter Tátrai, András Kiss, Zsuzsa Schaff, Ilona Kovalszky, Kornélia Baghy
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
decorin
ECM
colorectal carcinoma
RTK
signaling
liver metastasis
Online Access:https://www.mdpi.com/2218-273X/10/8/1199

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