Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications
The process of providing a pharmaceutical substance with a therapeutic effect in human or animals is known as drug delivery. There are several prospects to detect, treat, and heal of difficult illnesses for the development of nanoparticle-based medicines. A diversity of nanomaterials may be transfor...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-05-01
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| Series: | Results in Surfaces and Interfaces |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666845923000296 |
| _version_ | 1797802727670022144 |
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| author | Abdulbast Ali Khafoor Ayoub Sabir Karim S. Mohammad Sajadi |
| author_facet | Abdulbast Ali Khafoor Ayoub Sabir Karim S. Mohammad Sajadi |
| author_sort | Abdulbast Ali Khafoor |
| collection | DOAJ |
| description | The process of providing a pharmaceutical substance with a therapeutic effect in human or animals is known as drug delivery. There are several prospects to detect, treat, and heal of difficult illnesses for the development of nanoparticle-based medicines. A diversity of nanomaterials may be transformed into intelligent systems with discreet medicinal and imaging agents by manipulating their size, shape, surface modification, surface features, and materials employed. Such nanomaterials can show controlled release treatment by delivering medications to particular tissues. Additionally, a number of drug delivery methods based on liposomes have been developed as medical treatments. Improvements in the diagnosis and treatment of illnesses have been facilitated using nanoparticles as a tool. Tailored and extended medication administration based liposomal nanostructures improves patient compliance with less frequent doses while reducing drug-related damage. The most current developments in nanostructures synthesis for drug delivery and treatments with emphasis on liposomes are highlighted in this work. Because of their excellent biocompatibility, biodegradability, and minimal immunogenicity, liposomes are the most widely employed nanocarriers for a variety of hydrophobic and hydrophilic compounds that may be biologically operative. Additionally, liposomes have shown to improve the drug dissolution rate, regulated drug delivery, and ability to modify their surface. Liposomes have developed from traditional and immunological liposomes to stimuli-responsive and actively targeted liposomes based on their formation. To treat a variety of disorders, various liposomal-based drug delivery systems are presently medically licensed; therefore, in this review, the structure, content, production techniques, and some therapeutic uses of liposomes are addressed. |
| first_indexed | 2024-03-13T05:10:05Z |
| format | Article |
| id | doaj.art-8e816736423d401198b13efd3f4bbd02 |
| institution | Directory Open Access Journal |
| issn | 2666-8459 |
| language | English |
| last_indexed | 2024-03-13T05:10:05Z |
| publishDate | 2023-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Surfaces and Interfaces |
| spelling | doaj.art-8e816736423d401198b13efd3f4bbd022023-06-16T05:12:07ZengElsevierResults in Surfaces and Interfaces2666-84592023-05-0111100124Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applicationsAbdulbast Ali Khafoor0Ayoub Sabir Karim1S. Mohammad Sajadi2Physics Department, College of Education, Salahaddin University-Erbil 44002, Iraqi Kurdistan Region, IraqPhysics Department, College of Education, Salahaddin University-Erbil 44002, Iraqi Kurdistan Region, IraqDepartment of Nutrition, Cihan university-Erbil, Kurdistan Region, Iraq; Corresponding author.The process of providing a pharmaceutical substance with a therapeutic effect in human or animals is known as drug delivery. There are several prospects to detect, treat, and heal of difficult illnesses for the development of nanoparticle-based medicines. A diversity of nanomaterials may be transformed into intelligent systems with discreet medicinal and imaging agents by manipulating their size, shape, surface modification, surface features, and materials employed. Such nanomaterials can show controlled release treatment by delivering medications to particular tissues. Additionally, a number of drug delivery methods based on liposomes have been developed as medical treatments. Improvements in the diagnosis and treatment of illnesses have been facilitated using nanoparticles as a tool. Tailored and extended medication administration based liposomal nanostructures improves patient compliance with less frequent doses while reducing drug-related damage. The most current developments in nanostructures synthesis for drug delivery and treatments with emphasis on liposomes are highlighted in this work. Because of their excellent biocompatibility, biodegradability, and minimal immunogenicity, liposomes are the most widely employed nanocarriers for a variety of hydrophobic and hydrophilic compounds that may be biologically operative. Additionally, liposomes have shown to improve the drug dissolution rate, regulated drug delivery, and ability to modify their surface. Liposomes have developed from traditional and immunological liposomes to stimuli-responsive and actively targeted liposomes based on their formation. To treat a variety of disorders, various liposomal-based drug delivery systems are presently medically licensed; therefore, in this review, the structure, content, production techniques, and some therapeutic uses of liposomes are addressed.http://www.sciencedirect.com/science/article/pii/S2666845923000296SynthesisNanoliposomesDrug delivery systemsNanomedicines |
| spellingShingle | Abdulbast Ali Khafoor Ayoub Sabir Karim S. Mohammad Sajadi Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications Results in Surfaces and Interfaces Synthesis Nanoliposomes Drug delivery systems Nanomedicines |
| title | Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications |
| title_full | Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications |
| title_fullStr | Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications |
| title_full_unstemmed | Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications |
| title_short | Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications |
| title_sort | recent progress in synthesis of nano based liposomal drug delivery systems a glance to their medicinal applications |
| topic | Synthesis Nanoliposomes Drug delivery systems Nanomedicines |
| url | http://www.sciencedirect.com/science/article/pii/S2666845923000296 |
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