OPG/RANKL/RANK gene methylation among alcohol-induced femoral head necrosis in northern Chinese men

OPG/RANKL/RANK gene methylation among alcohol-induced femoral head necrosis in northern Chinese men

Abstract Background and purpose Alcohol-induced osteonecrosis of the femoral head (ONFH) is a complex and heterogeneous disease. Genetic factors and epigenetic modifications are one of the pathogenesis of the disease. However, the influence of epigenetic factors on the disease has not been systemati...

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Bibliographic Details
Main Authors: Tiantian Wang, Fei Wang, Tingting Liu, Menghu Sun, Feimeng An, Chang Liu, Ye Tian, Yuju Cao, Jianzhong Wang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Alcohol-induced osteonecrosis of the femoral head (ONFH)
OPG/RANKL/RANK
Methylation
CpG islands
Online Access:https://doi.org/10.1186/s13018-021-02356-y

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