Bacterial Abscess Formation Is Controlled by the Stringent Stress Response and Can Be Targeted Therapeutically

Bacterial Abscess Formation Is Controlled by the Stringent Stress Response and Can Be Targeted Therapeutically

Cutaneous abscess infections are difficult to treat with current therapies and alternatives to conventional antibiotics are needed. Understanding the regulatory mechanisms that govern abscess pathology should reveal therapeutic interventions for these recalcitrant infections. Here we demonstrated th...

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Bibliographic Details
Main Authors: Sarah C. Mansour, Daniel Pletzer, César de la Fuente-Núñez, Paul Kim, Gordon Y.C. Cheung, Hwang-Soo Joo, Michael Otto, Robert E.W. Hancock
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:EBioMedicine
Subjects:
Staphylococcus aureus
Pseudomonas aeruginosa
ppGpp
Cationic peptide
DJK-5
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416304248

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