Prognosing of myocardial infarction outcome in arterial hypertension patients
7-year prospective trial in 352 patients with essential hypertension (EH) was performed. The essence of the research was an original complex clinical-instrumental examination of hospitalized patients, with their annual follow-up in out- and in-patient conditions. Two clinical groups were formed: Gro...
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«FIRMA «SILICEA» LLC
2004-04-01
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Series: | Российский кардиологический журнал |
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Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1948 |
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author | V. N. Ardashev A. N. Fursov A. V. Konev O. A. Mantserova O. G. Chubarova E. F. Krivozubov |
author_facet | V. N. Ardashev A. N. Fursov A. V. Konev O. A. Mantserova O. G. Chubarova E. F. Krivozubov |
author_sort | V. N. Ardashev |
collection | DOAJ |
description | 7-year prospective trial in 352 patients with essential hypertension (EH) was performed. The essence of the research was an original complex clinical-instrumental examination of hospitalized patients, with their annual follow-up in out- and in-patient conditions. Two clinical groups were formed: Group 1 - patients with uncomplicated EH (n = 263); Group 2 - patients with EH complicated by myocardial infarction (MI) (n = 89). Prognostic decision was based on disease manifestations at baseline investigation. The final result, reflected in the classification, was MI registered in the 7-year follow-up period. Total prognostic accuracy of the classification, verified in the control group, reached 88. 5 %. IM predictors were: smoking, absence of regular antihypertensive therapy (AHT), increased peripheral vascular resistance, enhanced angiotensin 1 level, advanced left ventricular hypertrophy, with increased end-diastolic volume, low ejection fraction, high level of very low-density lipoprotein cholesterol, and myocardial ischemia during stress tests. Integral index of individual severity, calculated on the basis of prognostic decision rule, gives a possibility to perform the targeted prevention of cardiac complications. |
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id | doaj.art-8e8b8ec966634a888e13cd53a5a806d8 |
institution | Directory Open Access Journal |
issn | 1560-4071 2618-7620 |
language | Russian |
last_indexed | 2024-04-09T20:54:25Z |
publishDate | 2004-04-01 |
publisher | «FIRMA «SILICEA» LLC |
record_format | Article |
series | Российский кардиологический журнал |
spelling | doaj.art-8e8b8ec966634a888e13cd53a5a806d82023-03-29T21:23:11Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202004-04-010211151706Prognosing of myocardial infarction outcome in arterial hypertension patientsV. N. Ardashev0A. N. Fursov1A. V. Konev2O. A. Mantserova3O. G. Chubarova4E. F. Krivozubov5Главный военный клинический госпиталь им. Н.Н. БурденкоГлавный военный клинический госпиталь им. Н.Н. БурденкоГлавный военный клинический госпиталь им. Н.Н. БурденкоГлавный военный клинический госпиталь им. Н.Н. БурденкоГлавный военный клинический госпиталь им. Н.Н. БурденкоГлавный военный клинический госпиталь им. Н.Н. Бурденко7-year prospective trial in 352 patients with essential hypertension (EH) was performed. The essence of the research was an original complex clinical-instrumental examination of hospitalized patients, with their annual follow-up in out- and in-patient conditions. Two clinical groups were formed: Group 1 - patients with uncomplicated EH (n = 263); Group 2 - patients with EH complicated by myocardial infarction (MI) (n = 89). Prognostic decision was based on disease manifestations at baseline investigation. The final result, reflected in the classification, was MI registered in the 7-year follow-up period. Total prognostic accuracy of the classification, verified in the control group, reached 88. 5 %. IM predictors were: smoking, absence of regular antihypertensive therapy (AHT), increased peripheral vascular resistance, enhanced angiotensin 1 level, advanced left ventricular hypertrophy, with increased end-diastolic volume, low ejection fraction, high level of very low-density lipoprotein cholesterol, and myocardial ischemia during stress tests. Integral index of individual severity, calculated on the basis of prognostic decision rule, gives a possibility to perform the targeted prevention of cardiac complications.https://russjcardiol.elpub.ru/jour/article/view/1948essential hypertensionprognosiscomplicationmyocardial infarction |
spellingShingle | V. N. Ardashev A. N. Fursov A. V. Konev O. A. Mantserova O. G. Chubarova E. F. Krivozubov Prognosing of myocardial infarction outcome in arterial hypertension patients Российский кардиологический журнал essential hypertension prognosis complication myocardial infarction |
title | Prognosing of myocardial infarction outcome in arterial hypertension patients |
title_full | Prognosing of myocardial infarction outcome in arterial hypertension patients |
title_fullStr | Prognosing of myocardial infarction outcome in arterial hypertension patients |
title_full_unstemmed | Prognosing of myocardial infarction outcome in arterial hypertension patients |
title_short | Prognosing of myocardial infarction outcome in arterial hypertension patients |
title_sort | prognosing of myocardial infarction outcome in arterial hypertension patients |
topic | essential hypertension prognosis complication myocardial infarction |
url | https://russjcardiol.elpub.ru/jour/article/view/1948 |
work_keys_str_mv | AT vnardashev prognosingofmyocardialinfarctionoutcomeinarterialhypertensionpatients AT anfursov prognosingofmyocardialinfarctionoutcomeinarterialhypertensionpatients AT avkonev prognosingofmyocardialinfarctionoutcomeinarterialhypertensionpatients AT oamantserova prognosingofmyocardialinfarctionoutcomeinarterialhypertensionpatients AT ogchubarova prognosingofmyocardialinfarctionoutcomeinarterialhypertensionpatients AT efkrivozubov prognosingofmyocardialinfarctionoutcomeinarterialhypertensionpatients |