Adverse Toxic Effects of Tyrosine Kinase Inhibitors on Non-Target Zebrafish Liver (ZFL) Cells

Adverse Toxic Effects of Tyrosine Kinase Inhibitors on Non-Target Zebrafish Liver (ZFL) Cells

Over the past 20 years, numerous tyrosine kinase inhibitors (TKIs) have been introduced for targeted therapy of various types of malignancies. Due to frequent and increasing use, leading to eventual excretion with body fluids, their residues have been found in hospital and household wastewaters as w...

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Bibliographic Details
Main Authors: Katja Kološa, Bojana Žegura, Martina Štampar, Metka Filipič, Matjaž Novak
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
zebrafish liver cells
ZFL
tyrosine kinase inhibitors
cytotoxicity
cell cycle
genotoxicity
Online Access:https://www.mdpi.com/1422-0067/24/4/3894

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