Synthesis and Biological Evaluation of Disubstituted Pyrimidines as Selective 5-HT<sub>2C</sub> Agonists
Here, we describe the synthesis of disubstituted pyrimidine derivatives and their biological evaluation as selective 5-HT<sub>2C</sub> agonists. To improve selectivity for 5-HT<sub>2C</sub> over other subtypes, we synthesized two series of disubstituted pyrimidines with fluor...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-09-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/24/18/3234 |