Hyaluronidases Have Strong Hydrolytic Activity toward Chondroitin 4-Sulfate Comparable to that for Hyaluronan

Chondroitin sulfate (CS) chains are involved in the regulation of various biological processes. However, the mechanism underlying the catabolism of CS is not well understood. Hyaluronan (HA)-degrading enzymes, the hyaluronidases, are assumed to act at the initial stage of the degradation process, be...

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Bibliographic Details
Main Authors: Shuhei Yamada, Kazuyuki Sugahara, Shuji Mizumoto, Tomoko Honda, Tomoyuki Kaneiwa
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/2/4/549