Cluster analysis for localisation-based data sets: dos and don’ts when quantifying protein aggregates

Many proteins display a non-random distribution on the cell surface. From dimers to nanoscale clusters to large, micron-scale aggregations, these distributions regulate protein-protein interactions and signalling. Although these distributions show organisation on length-scales below the resolution l...

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Bibliographic Details
Main Authors: Luca Panconi, Dylan M. Owen, Juliette Griffié
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Bioinformatics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2023.1237551/full