Influence on Biological Behavior of Colon Cancer Stem Cells after RNA Interfering CD133

Influence on Biological Behavior of Colon Cancer Stem Cells after RNA Interfering CD133

OBJECTIVE To observe the effects of blocking CD133 gene expression and activation on biological characteristic of the colon cancer stem cells. METHODS CD133+ colon cancer stem cells (CCSCs) were separated from EpCAMhigh CD44+CCSCs through fluorescence-activated cell sorting (FACS). The proli...

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Bibliographic Details
Main Authors: Shao-lin LI, Mi CHEN, Mei LIU, Liang AI
Format: Article
Language:English
Published: China Anti-Cancer Association 2010-12-01
Series:Cancer Biology & Medicine
Subjects:
colonic neoplasms
stem cells
CD133 protein
mouse
RNA interference
biological behavior.
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/87

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