An Analysis of Tolerance and Early Survival Outcomes with Perioperative Modified FLOT in Gastric Cancers

An Analysis of Tolerance and Early Survival Outcomes with Perioperative Modified FLOT in Gastric Cancers

Abstract Anant Ramaswamy Purpose Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel (FLOT) is a current standard of care for locoregionally advanced gastric adeno...

Full description

Bibliographic Details
Main Authors:	Prabhat Bhargava, Sudeep Das, Vikas Ostwal, Sujay Srinivas, Manish Bhandare, Vikram Chaudhari, Munita Bal, Anoop Mantri, Akhil Kapoor, Shailesh V. Shrikhande, Anant Ramaswamy
Format:	Article
Language:	English
Published:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-04-01
Series:	South Asian Journal of Cancer
Subjects:	flot gastric cancer tolerance toxicity neoadjuvant adjuvant
Online Access:	http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1733349

Similar Items

Completion of FLOT Therapy, Regardless of Tumor Regression, Significantly Improves Overall Survival in Patients with Esophageal Adenocarcinoma
by: Björn-Ole Stüben, et al.
Published: (2022-02-01)

Pretreatment Modified Glasgow Prognostic Score for Predicting Prognosis and Survival in Elderly Patients with Gastric Cancer Treated with Perioperative FLOT
by: Ebru Melekoglu, et al.
Published: (2023-09-01)

Results of the observational prospective RealFLOT study
by: Elisa Giommoni, et al.
Published: (2021-10-01)

Impact of Signet-Ring Cell Histology in the Management of Patients with Non-Metastatic Gastric Cancer: Results from a Retrospective Multicenter Analysis Comparing FLOT Perioperative Chemotherapy vs. Surgery Followed by Adjuvant Chemotherapy
by: Riccardo Giampieri, et al.
Published: (2023-06-01)

Impact of neoadjuvant FLOT treatment of advanced gastric and gastroesophageal junction cancer following surgical therapy
by: Attila Paszt, et al.
Published: (2023-04-01)

FLOT1 promotes tumor development, induces epithelial–mesenchymal transition, and modulates the cell cycle by regulating the Erk/Akt signaling pathway in lung adenocarcinoma
by: Louqian Zhang, et al.
Published: (2019-04-01)

Perioperative Safety and Effectiveness of Neoadjuvant Therapy with Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel Plus Apatinib in Locally Advanced Gastric Cancer
by: Zhang Y, et al.
Published: (2021-03-01)

Interleukin-6 as a Predictive Factor of Pathological Response to FLOT Regimen Systemic Treatment in Locally Advanced Gastroesophageal Junction or Gastric Cancer Patients
by: Katarzyna Marcisz-Grzanka, et al.
Published: (2024-02-01)

The study of mechanism of miR-34c-5p targeting FLOT2 to regulate proliferation, migration and invasion of osteosarcoma cells
by: Yuqiang Wang, et al.
Published: (2019-12-01)

Circ-FOXM1 contributes to cell proliferation, invasion, and glycolysis and represses apoptosis in melanoma by regulating miR-143-3p/FLOT2 axis
by: Shan Tian, et al.
Published: (2020-03-01)

Circ_001569 regulates FLOT2 expression to promote the proliferation, migration, invasion and EMT of osteosarcoma cells through sponging miR-185-5p
by: Xiao Bin, et al.
Published: (2020-07-01)

The Flot2 component of the lipid raft changes localization during neural differentiation of P19C6 cells
by: Kei Hanafusa, et al.
Published: (2019-08-01)

Knockdown of PAF1 reduces cervical cancer cell proliferation, migration and invasion via retarding FLOT2-mediated MEK/ERK1/2 pathway
by: Bin Tang, et al.
Published: (2023-12-01)

Feasibility and Safety of Perioperative Chemotherapy With Fluorouracil Plus Leucovorin, Oxaliplatin, and Docetaxel for Locally Advanced Gastric Cancer Patients in China
by: Birendra Kumar Sah, et al.
Published: (2021-01-01)

Loss of Flot2 expression in deep cerebellar nuclei neurons of mice with Niemann-Pick disease type C
by: Tsu-I Chen, et al.
Published: (2023-07-01)

Chemotherapy-Induced Nausea and Vomiting in Gastrointestinal Cancer Patients: Do We Need to Revisit Guidelines?
by: Akhil Kapoor, et al.
Published: (2020-10-01)

Primary versus secondary antiemetic prophylaxis with NK1 receptor antagonists in patients affected by gastrointestinal malignancies and treated with a doublet or triplet combination regimen including oxaliplatin and/or irinotecan plus fluoropyrimidines: A propensity score matched analysis
by: Alessandro Parisi, et al.
Published: (2022-08-01)

MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway
by: Zhen Liang, et al.
Published: (2017-05-01)

Biomechanical importance of arch tension in athletic disciplines
by: Eutimio Armela-Suárez, et al.
Published: (2017-06-01)

The Prevalence of BRAF, PIK3CA, and RAS Mutations in Indian Patients with Colorectal Cancer
by: Omshree Shetty, et al.
Published: (2022-07-01)

RACE-trial: neoadjuvant radiochemotherapy versus chemotherapy for patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction - a randomized phase III joint study of the AIO, ARO and DGAV
by: Sylvie Lorenzen, et al.
Published: (2020-09-01)

Role of intraperitoneal chemotherapy in gastric cancer
by: Amir Parray, et al.
Published: (2021-03-01)

Modified FOLFIRINOX compared to Gemcitabine & nab-Paclitaxel in advanced pancreatic ductal adenocarcinoma - results of a match-pair analysis
by: Anant Ramaswamy, et al.
Published: (2023-01-01)

Cutting‐edge strategies for borderline resectable pancreatic cancer
by: Rajesh S. Shinde, et al.
Published: (2019-07-01)

Clinical case of pathological complete response of gastric cancer after one cycle of neoadjuvant chemotherapy with fot regimen
by: V. Yu. Skoropad, et al.
Published: (2023-01-01)

Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma
by: Maria Davern, et al.
Published: (2022-06-01)

Development of a New Tool to Assess the Quality of Life of Patients with Hand–Foot Syndrome Receiving Capecitabine-Based Therapy: A Pilot Study
by: Prathepa Jagdish, et al.
Published: (2022-01-01)

Polityka metropolii w kwestii militarnej i ekonomicznej obrony Nowej Hiszpanii za panowania dynastii Habsburgów (1516–1700). Zarys problematyki
by: Rafał Reichert
Published: (2016-12-01)

Perioperative Chemotherapy for Gastro-Esophageal or Gastric Cancer: Anthracyclin Triplets versus FLOT
by: Julie F. M. Geerts, et al.
Published: (2024-03-01)

Preventive HIPEC in combination with perioperative FLOT versus FLOT alone for resectable diffuse type gastric and gastroesophageal junction type II/III adenocarcinoma – the phase III “PREVENT”- (FLOT9) trial of the AIO /CAOGI /ACO
by: Thorsten O. Götze, et al.
Published: (2021-10-01)

Unraveling the spectrum of KIT mutations in gastrointestinal stromal tumors: An Indian Tertiary Cancer Center Experience
by: Trupti Pai, et al.
Published: (2017-01-01)

Retracted: Reduced levels of miR‐485‐5p in HPV‐infected cervical cancer promote cell proliferation and enhance invasion ability
by: Yuanyuan Dai, et al.
Published: (2020-07-01)

Pancreaticojejunostomy for Pancreatico-enteric Anastomosis after Pancreaticoduodenectomy: one procedure with multiple techniques.
by: Rajesh S Shinde, et al.
Published: (2020-12-01)

Perioperative FLOT chemotherapy plus surgery for oligometastatic esophagogastric adenocarcinoma: surgical outcome and overall survival
by: Mira Runkel, et al.
Published: (2021-01-01)

Presentation and Outcomes with First-Line Chemotherapy in Advanced Cholangiocarcinomas—A Relatively Rare Component of Biliary Tract Cancers in India
by: Prabhat G. Bhargava, et al.
Published: (2020-10-01)

Perioperative Chemotherapy with FLOT Scheme in Resectable Gastric Adenocarcinoma: A Preliminary Correlation between TRG and Radiomics
by: Giovanni Maria Garbarino, et al.
Published: (2021-10-01)

Economic evaluation of FLOT and ECF/ECX perioperative chemotherapy in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma
by: Xiaohui Zeng, et al.
Published: (2022-11-01)

Trastuzumab with FLOT Regimen for the Perioperative Treatment of Resectable HER2 + Advanced Gastric Cancer: A Retrospective Study
by: Tong G, et al.
Published: (2020-04-01)

Chemotherapy-Induced Alopecia: Can We Measure the Level of Distress in Oncology Patients? (The ALDO Study)
by: Prathepa Jagadish, et al.
Published: (2023-10-01)

Identification of novel raft marker protein, FlotP in Bacillus anthracis
by: Vikas Kumar Somani, et al.
Published: (2016-02-01)