Immunogenic Cell Death Enhances Immunotherapy of Diffuse Intrinsic Pontine Glioma: From Preclinical to Clinical Studies

Immunogenic Cell Death Enhances Immunotherapy of Diffuse Intrinsic Pontine Glioma: From Preclinical to Clinical Studies

Diffuse intrinsic pontine glioma (DIPG) is the most lethal tumor involving the pediatric central nervous system. The median survival of children that are diagnosed with DIPG is only 9 to 11 months. More than 200 clinical trials have failed to increase the survival outcomes using conventional cytotox...

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Bibliographic Details
Main Authors: Guohao Liu, Yanmei Qiu, Po Zhang, Zirong Chen, Sui Chen, Weida Huang, Baofeng Wang, Xingjiang Yu, Dongsheng Guo
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
diffuse intrinsic pontine glioma
immune microenvironment
immunotherapy
immunogenic cell death
damage associated molecular patterns
Online Access:https://www.mdpi.com/1999-4923/14/9/1762

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