CCL18 Expression Is Higher in a Glioblastoma Multiforme Tumor than in the Peritumoral Area and Causes the Migration of Tumor Cells Sensitized by Hypoxia

CCL18 Expression Is Higher in a Glioblastoma Multiforme Tumor than in the Peritumoral Area and Causes the Migration of Tumor Cells Sensitized by Hypoxia

Glioblastoma multiforme (GBM) is a brain tumor with a very poor prognosis. For this reason, researchers worldwide study the impact of the tumor microenvironment in GBM, such as the effect of chemokines. In the present study, we focus on the role of the chemokine CCL18 and its receptors in the GBM tu...

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Bibliographic Details
Main Authors: Szymon Grochans, Jan Korbecki, Donata Simińska, Wojciech Żwierełło, Sylwia Rzeszotek, Agnieszka Kolasa, Klaudyna Kojder, Maciej Tarnowski, Dariusz Chlubek, Irena Baranowska-Bosiacka
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
CCL18
PITPN3
CCR8
hypoxia
glioblastoma multiforme
tumor-associated macrophage
Online Access:https://www.mdpi.com/1422-0067/23/15/8536

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