Kaempferol attenuated diabetic nephropathy by reducing apoptosis and promoting autophagy through AMPK/mTOR pathways

Kaempferol attenuated diabetic nephropathy by reducing apoptosis and promoting autophagy through AMPK/mTOR pathways

IntroductionRenal podocyte injury, apoptosis and autophagy are involved in the occurrence and development of diabetic nephropathy (DN). Kaempferol (KPF) has the promotion of autophagy and inhibition of apoptosis properties in the development of miscellaneous diseases, but these functions in DN have...

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Bibliographic Details
Main Authors: Hongqin Sheng, Duo Zhang, Jiaqi Zhang, Yanmei Zhang, Zhaoyu Lu, Wei Mao, Xusheng Liu, Lei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Medicine
Subjects:
diabetic nephropathy
Kaempferol
apoptosis
autophagy
AMPK/mTOR pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.986825/full

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