Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to <italic toggle="yes">Candida</italic> Species

Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to <italic toggle="yes">Candida</italic> Species

ABSTRACT Invasive fungal infections constitute a lethal threat, with patient mortality as high as 90%. The incidence of invasive fungal infections is increasing, especially in the setting of patients receiving immunomodulatory agents, chemotherapy, or immunosuppressive medications following solid-or...

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Main Authors: Paige E. Negoro, Shuying Xu, Zeina Dagher, Alex Hopke, Jennifer L. Reedy, Michael B. Feldman, Nida S. Khan, Adam L. Viens, Natalie J. Alexander, Natalie J. Atallah, Allison K. Scherer, Richard A. Dutko, Jane Jeffery, John F. Kernien, J. Scott Fites, Jeniel E. Nett, Bruce S. Klein, Jatin M. Vyas, Daniel Irimia, David B. Sykes, Michael K. Mansour
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
neutrophils
spleen tyrosine kinase
Candida
fungus
Online Access:https://journals.asm.org/doi/10.1128/mBio.02043-19

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