NOTCH Signaling in Osteosarcoma
The combination of neoadjuvant chemotherapy and surgery has been promoted for the treatment of osteosarcoma; however, the local recurrence and lung metastasis rates remain high. Therefore, it is crucial to explore new therapeutic targets and strategies that are more effective. The NOTCH pathway is n...
Main Authors: | Zhenhao Zhang, Wei Wu, Zengwu Shao |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
|
Series: | Current Issues in Molecular Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/1467-3045/45/3/146 |
Similar Items
-
CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway
by: Jun Cheng, et al.
Published: (2022-07-01) -
ALKBH5 involves in osteosarcoma tumor progression by mediating Notch signaling
by: Dagui Chen, et al.
Published: (2023-03-01) -
Overexpression of Notch3 is associated with metastasis and poor prognosis in osteosarcoma patients
by: Tang XF, et al.
Published: (2019-01-01) -
Expressions of EZH2 and NOTCH3 pathway in osteosarcoma and their roles in osteosarcoma stem cells
by: Guangning Yan, et al.
Published: (2023-03-01) -
Cellular senescence-driven transcriptional reprogramming of the MAFB/NOTCH3 axis activates the PI3K/AKT pathway and promotes osteosarcoma progression
by: Zhenhao Zhang, et al.
Published: (2024-03-01)