Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study
Abstract Background We evaluated a magnetic resonance (MR)-conditional high-power microwave ablation system. Methods An ex vivo 1.5-T evaluation was conducted by varying the sequence (T1-weighted volume interpolated breath-hold examination, T1w-VIBE; T1-weighted fast low-angle shot, T1w-FLASH; T2-we...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-09-01
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| Series: | European Radiology Experimental |
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| Online Access: | http://link.springer.com/article/10.1186/s41747-019-0115-4 |
| _version_ | 1828797513351561216 |
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| author | Antonia Grimm Moritz Winkelmann Jakob Weiß Georg Gohla Gunnar Blumenstock Konstantin Nikolaou Stephan Clasen Rüdiger Hoffmann |
| author_facet | Antonia Grimm Moritz Winkelmann Jakob Weiß Georg Gohla Gunnar Blumenstock Konstantin Nikolaou Stephan Clasen Rüdiger Hoffmann |
| author_sort | Antonia Grimm |
| collection | DOAJ |
| description | Abstract Background We evaluated a magnetic resonance (MR)-conditional high-power microwave ablation system. Methods An ex vivo 1.5-T evaluation was conducted by varying the sequence (T1-weighted volume interpolated breath-hold examination, T1w-VIBE; T1-weighted fast low-angle shot, T1w-FLASH; T2-weighted turbo spin-echo, T2w-TSE), applicator angulation to B 0 (A-to-B 0), slice orientation, and encoding direction. Tip location error (TLE) and artefact diameters were measured, and influence of imaging parameters was assessed with analysis of variance and post hoc testing. Twenty-four ex vivo ablations were conducted in three bovine livers at 80 W and 120 W. Ablation durations were 5, 10, and 15 min. Ablation zones were compared for short-axis diameter (SAD), volume, and sphericity index (SI) with unpaired t test. Results The artefact pattern was similar for all sequences. The shaft artefact (4.4 ± 2.9 mm, mean ± standard deviation) was dependent on the sequence (p = 0.012) and the A-to-B 0 (p < 0.001); the largest shaft diameter was measured with T1w-FLASH (6.3 ± 3.4 mm) and with perpendicular A-to-B 0 (6.7 ± 2.4 mm). The tip artefact (1.6 ± 0.7 mm) was dependent on A-to-B 0 (p = 0.001); TLE was -2.6 ± 1.0 mm. Ablation results at the maximum setting (15 min, 120 W) were SAD = 42.0 ± 1.41 mm; volume = 56.78 ± 3.08 cm3, SI = 0.68 ± 0.05. In all ablations, SI ranged 0.68–0.75 with the smallest SI at 15 min and 120 W (p = 0.048). Conclusion The system produced sufficiently large ablation zones and the artefact was appropriate for MR-guided interventions. |
| first_indexed | 2024-12-12T04:42:26Z |
| format | Article |
| id | doaj.art-8eb05b657fab469cbb68fee2fb1afb32 |
| institution | Directory Open Access Journal |
| issn | 2509-9280 |
| language | English |
| last_indexed | 2024-12-12T04:42:26Z |
| publishDate | 2019-09-01 |
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| series | European Radiology Experimental |
| spelling | doaj.art-8eb05b657fab469cbb68fee2fb1afb322022-12-22T00:37:46ZengSpringerOpenEuropean Radiology Experimental2509-92802019-09-01311910.1186/s41747-019-0115-4Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo studyAntonia Grimm0Moritz Winkelmann1Jakob Weiß2Georg Gohla3Gunnar Blumenstock4Konstantin Nikolaou5Stephan Clasen6Rüdiger Hoffmann7Department of Diagnostic and Interventional Radiology, University Hospital of TübingenDepartment of Diagnostic and Interventional Radiology, University Hospital of TübingenDepartment of Diagnostic and Interventional Radiology, University Hospital of TübingenDepartment of Diagnostic and Interventional Radiology, University Hospital of TübingenInstitute for Clinical Epidemiology and Applied Biometry, University Hospital of TübingenDepartment of Diagnostic and Interventional Radiology, University Hospital of TübingenDepartment of Diagnostic and Interventional Radiology, University Hospital of TübingenDepartment of Diagnostic and Interventional Radiology, University Hospital of TübingenAbstract Background We evaluated a magnetic resonance (MR)-conditional high-power microwave ablation system. Methods An ex vivo 1.5-T evaluation was conducted by varying the sequence (T1-weighted volume interpolated breath-hold examination, T1w-VIBE; T1-weighted fast low-angle shot, T1w-FLASH; T2-weighted turbo spin-echo, T2w-TSE), applicator angulation to B 0 (A-to-B 0), slice orientation, and encoding direction. Tip location error (TLE) and artefact diameters were measured, and influence of imaging parameters was assessed with analysis of variance and post hoc testing. Twenty-four ex vivo ablations were conducted in three bovine livers at 80 W and 120 W. Ablation durations were 5, 10, and 15 min. Ablation zones were compared for short-axis diameter (SAD), volume, and sphericity index (SI) with unpaired t test. Results The artefact pattern was similar for all sequences. The shaft artefact (4.4 ± 2.9 mm, mean ± standard deviation) was dependent on the sequence (p = 0.012) and the A-to-B 0 (p < 0.001); the largest shaft diameter was measured with T1w-FLASH (6.3 ± 3.4 mm) and with perpendicular A-to-B 0 (6.7 ± 2.4 mm). The tip artefact (1.6 ± 0.7 mm) was dependent on A-to-B 0 (p = 0.001); TLE was -2.6 ± 1.0 mm. Ablation results at the maximum setting (15 min, 120 W) were SAD = 42.0 ± 1.41 mm; volume = 56.78 ± 3.08 cm3, SI = 0.68 ± 0.05. In all ablations, SI ranged 0.68–0.75 with the smallest SI at 15 min and 120 W (p = 0.048). Conclusion The system produced sufficiently large ablation zones and the artefact was appropriate for MR-guided interventions.http://link.springer.com/article/10.1186/s41747-019-0115-4Ablation techniquesCattleLiverMagnetic resonance imagingMicrowaves |
| spellingShingle | Antonia Grimm Moritz Winkelmann Jakob Weiß Georg Gohla Gunnar Blumenstock Konstantin Nikolaou Stephan Clasen Rüdiger Hoffmann Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study European Radiology Experimental Ablation techniques Cattle Liver Magnetic resonance imaging Microwaves |
| title | Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study |
| title_full | Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study |
| title_fullStr | Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study |
| title_full_unstemmed | Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study |
| title_short | Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study |
| title_sort | artefact and ablation performance of an mr conditional high power microwave system in bovine livers an ex vivo study |
| topic | Ablation techniques Cattle Liver Magnetic resonance imaging Microwaves |
| url | http://link.springer.com/article/10.1186/s41747-019-0115-4 |
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