ADRENAL cystic lymphangioma PRESENTING as a nonfunctioning adrenal carcinoma in a 45-year-old male: Case report
Adrenal cystic lymphangiomas are unusual entities with a very low prevalence that are typically discovered incidentally. We describe a 45-year-old male known for hypertension that was referred to our endocrinology department for right adrenal incidentaloma. Seven months prior referral, he presented...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-06-01
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| Series: | Journal of Clinical and Translational Endocrinology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214624520300071 |
| _version_ | 1828418597272158208 |
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| author | Lam-Chung César Ernesto Rodríguez Orihuela Diana Lizbeth Clemente-Gutiérrez Uriel Arízaga-Ramírez Rebeca Cuevas-Ramos Daniel Almeda-Valdés Paloma De Anda González Jazmín Gamboa-Domínguez Armando |
| author_facet | Lam-Chung César Ernesto Rodríguez Orihuela Diana Lizbeth Clemente-Gutiérrez Uriel Arízaga-Ramírez Rebeca Cuevas-Ramos Daniel Almeda-Valdés Paloma De Anda González Jazmín Gamboa-Domínguez Armando |
| author_sort | Lam-Chung César Ernesto |
| collection | DOAJ |
| description | Adrenal cystic lymphangiomas are unusual entities with a very low prevalence that are typically discovered incidentally. We describe a 45-year-old male known for hypertension that was referred to our endocrinology department for right adrenal incidentaloma. Seven months prior referral, he presented right hypochondrium pain, vomiting and nausea and imaging studies included a computer tomography that revealed an irregular-shaped right adrenal lesion (42 × 23 mm), with scattered calcifications in the medial branch and heterogenous contrast enhancement and contrast-enhanced computer tomography showed an absolute wash-out of 28% and hyperattenuating areas (>90 HU). Physical examination was unremarkable. Hormonal studies were all within normal range. Due to the findings of imaging studies and lack of biochemical findings a presumptive diagnosis of non-producing adrenal carcinoma was made. Laparoscopic of right adrenalectomy was carried out. Macroscopic appearance of the resected right adrenal surface showed a 3.0 × 2.5 cm whitish-grayish multicystic lesion with solid areas that replaced all adrenal medulla and almost all the cortex. Microscopic examination revealed multiple cystic channels lined with endothelial cells without atypia or mitotic figures. On immunohistochemical examination, anti-calretinin, anti-D2-40 and anti-Factor VIII were all positive confirming the diagnosis of adrenal cystic lymphangioma. It is a rare pathology that should be considered as part of the differential diagnosis during the evaluation of adrenal gland masses. |
| first_indexed | 2024-12-10T14:40:25Z |
| format | Article |
| id | doaj.art-8eb7fb013f9940aa89b03142d22a8c86 |
| institution | Directory Open Access Journal |
| issn | 2214-6245 |
| language | English |
| last_indexed | 2024-12-10T14:40:25Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Clinical and Translational Endocrinology Case Reports |
| spelling | doaj.art-8eb7fb013f9940aa89b03142d22a8c862022-12-22T01:44:43ZengElsevierJournal of Clinical and Translational Endocrinology Case Reports2214-62452020-06-0116100062ADRENAL cystic lymphangioma PRESENTING as a nonfunctioning adrenal carcinoma in a 45-year-old male: Case reportLam-Chung César Ernesto0Rodríguez Orihuela Diana Lizbeth1Clemente-Gutiérrez Uriel2Arízaga-Ramírez Rebeca3Cuevas-Ramos Daniel4Almeda-Valdés Paloma5De Anda González Jazmín6Gamboa-Domínguez Armando7Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MexicoDepartment of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MexicoDepartment of Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MexicoDepartment of Radiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MexicoDepartment of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MexicoDepartment of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MexicoDepartment of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MexicoDepartment of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico; Corresponding author. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Sección XVI, Tlalpan, 14000, México City, Mexico.Adrenal cystic lymphangiomas are unusual entities with a very low prevalence that are typically discovered incidentally. We describe a 45-year-old male known for hypertension that was referred to our endocrinology department for right adrenal incidentaloma. Seven months prior referral, he presented right hypochondrium pain, vomiting and nausea and imaging studies included a computer tomography that revealed an irregular-shaped right adrenal lesion (42 × 23 mm), with scattered calcifications in the medial branch and heterogenous contrast enhancement and contrast-enhanced computer tomography showed an absolute wash-out of 28% and hyperattenuating areas (>90 HU). Physical examination was unremarkable. Hormonal studies were all within normal range. Due to the findings of imaging studies and lack of biochemical findings a presumptive diagnosis of non-producing adrenal carcinoma was made. Laparoscopic of right adrenalectomy was carried out. Macroscopic appearance of the resected right adrenal surface showed a 3.0 × 2.5 cm whitish-grayish multicystic lesion with solid areas that replaced all adrenal medulla and almost all the cortex. Microscopic examination revealed multiple cystic channels lined with endothelial cells without atypia or mitotic figures. On immunohistochemical examination, anti-calretinin, anti-D2-40 and anti-Factor VIII were all positive confirming the diagnosis of adrenal cystic lymphangioma. It is a rare pathology that should be considered as part of the differential diagnosis during the evaluation of adrenal gland masses.http://www.sciencedirect.com/science/article/pii/S2214624520300071Adrenal glandLymphangiomaAdrenal cortical carcinoma |
| spellingShingle | Lam-Chung César Ernesto Rodríguez Orihuela Diana Lizbeth Clemente-Gutiérrez Uriel Arízaga-Ramírez Rebeca Cuevas-Ramos Daniel Almeda-Valdés Paloma De Anda González Jazmín Gamboa-Domínguez Armando ADRENAL cystic lymphangioma PRESENTING as a nonfunctioning adrenal carcinoma in a 45-year-old male: Case report Journal of Clinical and Translational Endocrinology Case Reports Adrenal gland Lymphangioma Adrenal cortical carcinoma |
| title | ADRENAL cystic lymphangioma PRESENTING as a nonfunctioning adrenal carcinoma in a 45-year-old male: Case report |
| title_full | ADRENAL cystic lymphangioma PRESENTING as a nonfunctioning adrenal carcinoma in a 45-year-old male: Case report |
| title_fullStr | ADRENAL cystic lymphangioma PRESENTING as a nonfunctioning adrenal carcinoma in a 45-year-old male: Case report |
| title_full_unstemmed | ADRENAL cystic lymphangioma PRESENTING as a nonfunctioning adrenal carcinoma in a 45-year-old male: Case report |
| title_short | ADRENAL cystic lymphangioma PRESENTING as a nonfunctioning adrenal carcinoma in a 45-year-old male: Case report |
| title_sort | adrenal cystic lymphangioma presenting as a nonfunctioning adrenal carcinoma in a 45 year old male case report |
| topic | Adrenal gland Lymphangioma Adrenal cortical carcinoma |
| url | http://www.sciencedirect.com/science/article/pii/S2214624520300071 |
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