Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial

Objectives: This study aimed to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) and xylitol chewing gums, and probiotic yogurt, as chemical plaque control strategies, on periodontal parameters. Materials and Methods: This randomized clinical trial evaluated 120 el...

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Main Authors: Vajihe Barati, Maryam Mehrabkhani, Iman Parisay, Niayesh Mastoori
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2021-09-01
Series:Frontiers in Dentistry
Subjects:
Online Access:https://fid.tums.ac.ir/index.php/fid/article/view/3755
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author Vajihe Barati
Maryam Mehrabkhani
Iman Parisay
Niayesh Mastoori
author_facet Vajihe Barati
Maryam Mehrabkhani
Iman Parisay
Niayesh Mastoori
author_sort Vajihe Barati
collection DOAJ
description Objectives: This study aimed to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) and xylitol chewing gums, and probiotic yogurt, as chemical plaque control strategies, on periodontal parameters. Materials and Methods: This randomized clinical trial evaluated 120 eligible dental students that were randomly divided into four groups (n=30) for use of (I) CPP-ACP chewing gum, (II) xylitol chewing gum, (III) probiotic yogurt, and (IV) chlorhexidine (CHX) mouthwash. The oral hygiene index-simplified (OHI-S), Silness and Loe gingival index (GI), and Silness and Loe modified plaque index (PI) were measured before and on days 15 and 30 after using the products. Paired t-test or its non-parametric equivalent was used to analyze the parameters after the intervention compared with baseline. The study groups were compared using one-way ANOVA or its non-parametric equivalent. Results: The OHI-S did not change over time, and most participants had a good OHI-S. The CHX group had the most favorable, and the probiotic yogurt group had the least favorable GI. Pairwise comparisons of the groups did not reveal a significant difference in GI between the CPP-ACP gum and CHX groups (P>0.05). CHX caused the greatest improvement in PI, with significant differences with other groups. Conclusion: CHX was the most effective for improvement of periodontal parameters followed by CPP-ACP, which showed better results compared with other groups.
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spelling doaj.art-8eb8e445c44548a0aa8b98d40d9580742022-12-21T19:24:59ZengTehran University of Medical SciencesFrontiers in Dentistry2676-296X2021-09-011810.18502/fid.v18i35.7339Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical TrialVajihe Barati0Maryam Mehrabkhani1Iman Parisay2Niayesh Mastoori3residentaaAAAaaObjectives: This study aimed to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) and xylitol chewing gums, and probiotic yogurt, as chemical plaque control strategies, on periodontal parameters. Materials and Methods: This randomized clinical trial evaluated 120 eligible dental students that were randomly divided into four groups (n=30) for use of (I) CPP-ACP chewing gum, (II) xylitol chewing gum, (III) probiotic yogurt, and (IV) chlorhexidine (CHX) mouthwash. The oral hygiene index-simplified (OHI-S), Silness and Loe gingival index (GI), and Silness and Loe modified plaque index (PI) were measured before and on days 15 and 30 after using the products. Paired t-test or its non-parametric equivalent was used to analyze the parameters after the intervention compared with baseline. The study groups were compared using one-way ANOVA or its non-parametric equivalent. Results: The OHI-S did not change over time, and most participants had a good OHI-S. The CHX group had the most favorable, and the probiotic yogurt group had the least favorable GI. Pairwise comparisons of the groups did not reveal a significant difference in GI between the CPP-ACP gum and CHX groups (P>0.05). CHX caused the greatest improvement in PI, with significant differences with other groups. Conclusion: CHX was the most effective for improvement of periodontal parameters followed by CPP-ACP, which showed better results compared with other groups.https://fid.tums.ac.ir/index.php/fid/article/view/3755Casein phosphopeptide-amorphous calcium phosphate nanocomplex; Xylitol; Probiotics; Periodontal Diseases; Chlorhexidine
spellingShingle Vajihe Barati
Maryam Mehrabkhani
Iman Parisay
Niayesh Mastoori
Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial
Frontiers in Dentistry
Casein phosphopeptide-amorphous calcium phosphate nanocomplex; Xylitol; Probiotics; Periodontal Diseases; Chlorhexidine
title Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial
title_full Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial
title_fullStr Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial
title_full_unstemmed Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial
title_short Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial
title_sort effect of casein phosphopeptide amorphous calcium phosphate and xylitol chewing gums and probiotic yogurt on periodontal parameters a randomized clinical trial
topic Casein phosphopeptide-amorphous calcium phosphate nanocomplex; Xylitol; Probiotics; Periodontal Diseases; Chlorhexidine
url https://fid.tums.ac.ir/index.php/fid/article/view/3755
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