Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial
Objectives: This study aimed to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) and xylitol chewing gums, and probiotic yogurt, as chemical plaque control strategies, on periodontal parameters. Materials and Methods: This randomized clinical trial evaluated 120 el...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2021-09-01
|
Series: | Frontiers in Dentistry |
Subjects: | |
Online Access: | https://fid.tums.ac.ir/index.php/fid/article/view/3755 |
_version_ | 1818999562464919552 |
---|---|
author | Vajihe Barati Maryam Mehrabkhani Iman Parisay Niayesh Mastoori |
author_facet | Vajihe Barati Maryam Mehrabkhani Iman Parisay Niayesh Mastoori |
author_sort | Vajihe Barati |
collection | DOAJ |
description | Objectives: This study aimed to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) and xylitol chewing gums, and probiotic yogurt, as chemical plaque control strategies, on periodontal parameters.
Materials and Methods: This randomized clinical trial evaluated 120 eligible dental students that were randomly divided into four groups (n=30) for use of (I) CPP-ACP chewing gum, (II) xylitol chewing gum, (III) probiotic yogurt, and (IV) chlorhexidine (CHX) mouthwash. The oral hygiene index-simplified (OHI-S), Silness and Loe gingival index (GI), and Silness and Loe modified plaque index (PI) were measured before and on days 15 and 30 after using the products. Paired t-test or its non-parametric equivalent was used to analyze the parameters after the intervention compared with baseline. The study groups were compared using one-way ANOVA or its non-parametric equivalent.
Results: The OHI-S did not change over time, and most participants had a good OHI-S. The CHX group had the most favorable, and the probiotic yogurt group had the least favorable GI. Pairwise comparisons of the groups did not reveal a significant difference in GI between the CPP-ACP gum and CHX groups (P>0.05). CHX caused the greatest improvement in PI, with significant differences with other groups.
Conclusion: CHX was the most effective for improvement of periodontal parameters followed by CPP-ACP, which showed better results compared with other groups. |
first_indexed | 2024-12-20T22:19:24Z |
format | Article |
id | doaj.art-8eb8e445c44548a0aa8b98d40d958074 |
institution | Directory Open Access Journal |
issn | 2676-296X |
language | English |
last_indexed | 2024-12-20T22:19:24Z |
publishDate | 2021-09-01 |
publisher | Tehran University of Medical Sciences |
record_format | Article |
series | Frontiers in Dentistry |
spelling | doaj.art-8eb8e445c44548a0aa8b98d40d9580742022-12-21T19:24:59ZengTehran University of Medical SciencesFrontiers in Dentistry2676-296X2021-09-011810.18502/fid.v18i35.7339Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical TrialVajihe Barati0Maryam Mehrabkhani1Iman Parisay2Niayesh Mastoori3residentaaAAAaaObjectives: This study aimed to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) and xylitol chewing gums, and probiotic yogurt, as chemical plaque control strategies, on periodontal parameters. Materials and Methods: This randomized clinical trial evaluated 120 eligible dental students that were randomly divided into four groups (n=30) for use of (I) CPP-ACP chewing gum, (II) xylitol chewing gum, (III) probiotic yogurt, and (IV) chlorhexidine (CHX) mouthwash. The oral hygiene index-simplified (OHI-S), Silness and Loe gingival index (GI), and Silness and Loe modified plaque index (PI) were measured before and on days 15 and 30 after using the products. Paired t-test or its non-parametric equivalent was used to analyze the parameters after the intervention compared with baseline. The study groups were compared using one-way ANOVA or its non-parametric equivalent. Results: The OHI-S did not change over time, and most participants had a good OHI-S. The CHX group had the most favorable, and the probiotic yogurt group had the least favorable GI. Pairwise comparisons of the groups did not reveal a significant difference in GI between the CPP-ACP gum and CHX groups (P>0.05). CHX caused the greatest improvement in PI, with significant differences with other groups. Conclusion: CHX was the most effective for improvement of periodontal parameters followed by CPP-ACP, which showed better results compared with other groups.https://fid.tums.ac.ir/index.php/fid/article/view/3755Casein phosphopeptide-amorphous calcium phosphate nanocomplex; Xylitol; Probiotics; Periodontal Diseases; Chlorhexidine |
spellingShingle | Vajihe Barati Maryam Mehrabkhani Iman Parisay Niayesh Mastoori Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial Frontiers in Dentistry Casein phosphopeptide-amorphous calcium phosphate nanocomplex; Xylitol; Probiotics; Periodontal Diseases; Chlorhexidine |
title | Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial |
title_full | Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial |
title_fullStr | Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial |
title_full_unstemmed | Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial |
title_short | Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial |
title_sort | effect of casein phosphopeptide amorphous calcium phosphate and xylitol chewing gums and probiotic yogurt on periodontal parameters a randomized clinical trial |
topic | Casein phosphopeptide-amorphous calcium phosphate nanocomplex; Xylitol; Probiotics; Periodontal Diseases; Chlorhexidine |
url | https://fid.tums.ac.ir/index.php/fid/article/view/3755 |
work_keys_str_mv | AT vajihebarati effectofcaseinphosphopeptideamorphouscalciumphosphateandxylitolchewinggumsandprobioticyogurtonperiodontalparametersarandomizedclinicaltrial AT maryammehrabkhani effectofcaseinphosphopeptideamorphouscalciumphosphateandxylitolchewinggumsandprobioticyogurtonperiodontalparametersarandomizedclinicaltrial AT imanparisay effectofcaseinphosphopeptideamorphouscalciumphosphateandxylitolchewinggumsandprobioticyogurtonperiodontalparametersarandomizedclinicaltrial AT niayeshmastoori effectofcaseinphosphopeptideamorphouscalciumphosphateandxylitolchewinggumsandprobioticyogurtonperiodontalparametersarandomizedclinicaltrial |