Nasal high-flow oxygen versus noninvasive ventilation in acute exacerbation of COPD: protocol for a randomised noninferiority clinical trial

Nasal high-flow oxygen versus noninvasive ventilation in acute exacerbation of COPD: protocol for a randomised noninferiority clinical trial

Background Noninvasive ventilation (NIV) is considered as the first-line treatment for acute exacerbation of COPD (AECOPD) complicated by respiratory acidosis. Recent studies demonstrate a role of nasal high-flow oxygen (NHF) in AECOPD as an alternative treatment in patients intolerant to NIV or wit...

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Main Authors: Athanasia Papalampidou, Eleni Bibaki, Stylianos Boutlas, Ioannis Pantazopoulos, Nikolaos Athanasiou, Melanie Moylan, Vasileios Vlachakos, Vasileios Grigoropoulos, Konstantinos Eleftheriou, Zoe Daniil, Konstantinos Gourgoulianis, Ioannis Kalomenidis, Spyros Zakynthinos, Eleni Ischaki
Format: Article
Language:English
Published: European Respiratory Society 2020-10-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/6/4/00114-2020.full

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