Fumarase mediates transcriptional response to nutrient stress

Limited supply of nutrient normally causes cell growth arrest. Our recent study (Nat Cell Biol. (7):833-843) shows that fumarase (FH), a key enzyme responsible for the conversion between fumarate and malate in tricarboxylic acid cycle, is importantly involved in the cellular response to nutrient con...

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Main Authors: Qin Zhao, Yuhui Jiang
Format: Article
Language:English
Published: Shared Science Publishers OG 2017-10-01
Series:Cell Stress
Subjects:
Online Access:http://www.cell-stress.com/researcharticles/fumarase-mediates-transcriptional-response-to-nutrient-stress/
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author Qin Zhao
Yuhui Jiang
author_facet Qin Zhao
Yuhui Jiang
author_sort Qin Zhao
collection DOAJ
description Limited supply of nutrient normally causes cell growth arrest. Our recent study (Nat Cell Biol. (7):833-843) shows that fumarase (FH), a key enzyme responsible for the conversion between fumarate and malate in tricarboxylic acid cycle, is importantly involved in the cellular response to nutrient condition.
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spelling doaj.art-8eb9aefd7d38433f8554f3b34db8ba352022-12-21T23:59:56ZengShared Science Publishers OGCell Stress2523-02042017-10-0111686910.15698/cst2017.10.107Fumarase mediates transcriptional response to nutrient stressQin Zhao0Yuhui Jiang1The Institute of Cell Metabolism, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai 200080, China.The Institute of Cell Metabolism, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai 200080, China.Limited supply of nutrient normally causes cell growth arrest. Our recent study (Nat Cell Biol. (7):833-843) shows that fumarase (FH), a key enzyme responsible for the conversion between fumarate and malate in tricarboxylic acid cycle, is importantly involved in the cellular response to nutrient condition.http://www.cell-stress.com/researcharticles/fumarase-mediates-transcriptional-response-to-nutrient-stress/fumarasecellular responsenutrient condition
spellingShingle Qin Zhao
Yuhui Jiang
Fumarase mediates transcriptional response to nutrient stress
Cell Stress
fumarase
cellular response
nutrient condition
title Fumarase mediates transcriptional response to nutrient stress
title_full Fumarase mediates transcriptional response to nutrient stress
title_fullStr Fumarase mediates transcriptional response to nutrient stress
title_full_unstemmed Fumarase mediates transcriptional response to nutrient stress
title_short Fumarase mediates transcriptional response to nutrient stress
title_sort fumarase mediates transcriptional response to nutrient stress
topic fumarase
cellular response
nutrient condition
url http://www.cell-stress.com/researcharticles/fumarase-mediates-transcriptional-response-to-nutrient-stress/
work_keys_str_mv AT qinzhao fumarasemediatestranscriptionalresponsetonutrientstress
AT yuhuijiang fumarasemediatestranscriptionalresponsetonutrientstress