Distribution patterns of foot and ankle tumors: a university tumor institute experience
Abstract Background Bone and soft tissue masses of the foot and ankle are not particularly rare but true neoplasia has to be strictly differentiated from pseudotumorous lesions. Diagnosis is often delayed as diagnostic errors are more common than in other regions. Awareness for this localization of...
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| Format: | Article |
| Language: | English |
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BMC
2018-07-01
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| Series: | BMC Cancer |
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| Online Access: | http://link.springer.com/article/10.1186/s12885-018-4648-3 |
| _version_ | 1819090312497201152 |
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| author | Andreas Toepfer Norbert Harrasser Maximiliane Recker Ulrich Lenze Florian Pohlig Ludger Gerdesmeyer Rüdiger von Eisenhart-Rothe |
| author_facet | Andreas Toepfer Norbert Harrasser Maximiliane Recker Ulrich Lenze Florian Pohlig Ludger Gerdesmeyer Rüdiger von Eisenhart-Rothe |
| author_sort | Andreas Toepfer |
| collection | DOAJ |
| description | Abstract Background Bone and soft tissue masses of the foot and ankle are not particularly rare but true neoplasia has to be strictly differentiated from pseudotumorous lesions. Diagnosis is often delayed as diagnostic errors are more common than in other regions. Awareness for this localization of musculoskeletal tumors is not very high and neoplasia is often not considered. The purpose of this study is to provide detailed information on the incidence and distribution patterns of foot and ankle tumors of a university tumor institute and propose a simple definition to facilitate comparison of future investigations. Methods As part of a retrospective, single-centre study, the data of patients that were treated for foot and ankle tumors between June 1997 and December 2015 in a musculoskeletal tumor centre were analyzed regarding epidemiologic information, entity and localization. Included were all cases with a true tumor of the foot and ankle. Exclusion criteria were incomplete information on the patient or entity (e.g. histopathological diagnosis) and all pseudotumoral lesions. Results Out of 7487 musculoskeletal tumors, 413 cases (5,52%) of tumors of the foot and ankle in 409 patients were included (215 male and 198 female patients). The average age of the affected patients was 36 ± 18y (min.3y, max.92y). Two hundred sixty-six tumors involved the bone (64%), among them 231 (87%) benign and 35 (13%) malignant. There were 147 soft tissue tumors (36%), 104 (71%) were benign, 43 (29%) malignant. The most common benign osseous tumor lesions included simple bone cysts, enchondroma and osteochondroma. By far the most common malignant bone tumor was chondrosarcoma. Common benign soft tissue tumors included pigmented villo-nodular synovitis, superifcial fibromatosis and schwannoma whereas the most common malignant members were synovial sarcoma and myxofibrosarcoma. Regarding anatomical localization, the hindfoot was affected most often. Conclusions Knowledge of incidence and distribution patterns of foot and ankle tumors will help to correctly assess unclear masses and initiate the right steps in further diagnostics and treatment. Unawareness can lead to delayed diagnosis and inadequate treatment with serious consequences for the affected patient. |
| first_indexed | 2024-12-21T22:21:50Z |
| format | Article |
| id | doaj.art-8ebba454bae14fd3a8bd4192701b810d |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-21T22:21:50Z |
| publishDate | 2018-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-8ebba454bae14fd3a8bd4192701b810d2022-12-21T18:48:19ZengBMCBMC Cancer1471-24072018-07-0118111010.1186/s12885-018-4648-3Distribution patterns of foot and ankle tumors: a university tumor institute experienceAndreas Toepfer0Norbert Harrasser1Maximiliane Recker2Ulrich Lenze3Florian Pohlig4Ludger Gerdesmeyer5Rüdiger von Eisenhart-Rothe6Klinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar der Technischen, Universität MünchenKlinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar der Technischen, Universität MünchenKlinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar der Technischen, Universität MünchenKlinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar der Technischen, Universität MünchenKlinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar der Technischen, Universität MünchenUniversitätsklinikum Schleswig Holstein, Campus Kiel, Sektion für Onkologische und Rheumatologische Orthopädie in der Klinik für UnfallchirurgieKlinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar der Technischen, Universität MünchenAbstract Background Bone and soft tissue masses of the foot and ankle are not particularly rare but true neoplasia has to be strictly differentiated from pseudotumorous lesions. Diagnosis is often delayed as diagnostic errors are more common than in other regions. Awareness for this localization of musculoskeletal tumors is not very high and neoplasia is often not considered. The purpose of this study is to provide detailed information on the incidence and distribution patterns of foot and ankle tumors of a university tumor institute and propose a simple definition to facilitate comparison of future investigations. Methods As part of a retrospective, single-centre study, the data of patients that were treated for foot and ankle tumors between June 1997 and December 2015 in a musculoskeletal tumor centre were analyzed regarding epidemiologic information, entity and localization. Included were all cases with a true tumor of the foot and ankle. Exclusion criteria were incomplete information on the patient or entity (e.g. histopathological diagnosis) and all pseudotumoral lesions. Results Out of 7487 musculoskeletal tumors, 413 cases (5,52%) of tumors of the foot and ankle in 409 patients were included (215 male and 198 female patients). The average age of the affected patients was 36 ± 18y (min.3y, max.92y). Two hundred sixty-six tumors involved the bone (64%), among them 231 (87%) benign and 35 (13%) malignant. There were 147 soft tissue tumors (36%), 104 (71%) were benign, 43 (29%) malignant. The most common benign osseous tumor lesions included simple bone cysts, enchondroma and osteochondroma. By far the most common malignant bone tumor was chondrosarcoma. Common benign soft tissue tumors included pigmented villo-nodular synovitis, superifcial fibromatosis and schwannoma whereas the most common malignant members were synovial sarcoma and myxofibrosarcoma. Regarding anatomical localization, the hindfoot was affected most often. Conclusions Knowledge of incidence and distribution patterns of foot and ankle tumors will help to correctly assess unclear masses and initiate the right steps in further diagnostics and treatment. Unawareness can lead to delayed diagnosis and inadequate treatment with serious consequences for the affected patient.http://link.springer.com/article/10.1186/s12885-018-4648-3Foot tumorMusculoskeletal tumorBone sarcomaSoft tissue sarcomaCalcaneal bone cyst |
| spellingShingle | Andreas Toepfer Norbert Harrasser Maximiliane Recker Ulrich Lenze Florian Pohlig Ludger Gerdesmeyer Rüdiger von Eisenhart-Rothe Distribution patterns of foot and ankle tumors: a university tumor institute experience BMC Cancer Foot tumor Musculoskeletal tumor Bone sarcoma Soft tissue sarcoma Calcaneal bone cyst |
| title | Distribution patterns of foot and ankle tumors: a university tumor institute experience |
| title_full | Distribution patterns of foot and ankle tumors: a university tumor institute experience |
| title_fullStr | Distribution patterns of foot and ankle tumors: a university tumor institute experience |
| title_full_unstemmed | Distribution patterns of foot and ankle tumors: a university tumor institute experience |
| title_short | Distribution patterns of foot and ankle tumors: a university tumor institute experience |
| title_sort | distribution patterns of foot and ankle tumors a university tumor institute experience |
| topic | Foot tumor Musculoskeletal tumor Bone sarcoma Soft tissue sarcoma Calcaneal bone cyst |
| url | http://link.springer.com/article/10.1186/s12885-018-4648-3 |
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