Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in Rats
Background and purpose: Transgenic rice is a type of rice that its genetic sequence has been changed to improve its quantity and quality. Bt (Bacillus thuringiensis) transgenic rice expresses Cry1Ab protein and is named Tarom Molaii. There are no studies on the effect of this type of transgenic rice...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Mazandaran University of Medical Sciences
2022-08-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-17619-en.html |
| _version_ | 1797893234303696896 |
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| author | Bahador Hajimohammadi Gilda Eslami Hengameh Zandi Saeedeh Sadat Hosseini Mehrnoosh Shirdeli Elahe Loni Salman Ahmadian Vahideh Askari Maryam Sheykhzadegan Raziyeh Barzegar-bafroui Hossein Fallahzadeh Mahmoud Vakili |
| author_facet | Bahador Hajimohammadi Gilda Eslami Hengameh Zandi Saeedeh Sadat Hosseini Mehrnoosh Shirdeli Elahe Loni Salman Ahmadian Vahideh Askari Maryam Sheykhzadegan Raziyeh Barzegar-bafroui Hossein Fallahzadeh Mahmoud Vakili |
| author_sort | Bahador Hajimohammadi |
| collection | DOAJ |
| description | Background and purpose: Transgenic rice is a type of rice that its genetic sequence has been changed to improve its quantity and quality. Bt (Bacillus thuringiensis) transgenic rice expresses Cry1Ab protein and is named Tarom Molaii. There are no studies on the effect of this type of transgenic rice on gastrointestinal health in Iran, so, this study investigated the effect of Tarom Molaii transgenic rice on common microbial flora of rat intestine.
Materials and methods: In this experimental study, 24 Sprague Dawley (SD) rats received transgenic and non-transgenic rice in their diets for 90 days and were compared with the control group that received standard rat diet. The number of Escherichia coli, Bifidobacterium, Lactobacillus, and Enterococcus bacteria and the total number of aerobic and anaerobic bacteria in fecal samples were examined in jejunum, ileum, and duodenum samples on days 60, 90, and after killing the rats.
Results: The study showed that except for the total number of anaerobic bacteria in the stool sample on day 90, there was no significant relationship between the study groups and the number of bacteria (P>0.05). There was an increase in the number of intestinal Lactobacillus in the transgenic rice-fed group and a decrease in the number of anaerobic bacteria in the transgenic rice-fed group compared with the control group and the non-transgenic rice-fed group.
Conclusion: Consumption of transgenic rice in current study had no considerable effect on the number of common bacteria in the intestinal normal flora. But, long-term studies are needed in other laboratory animals. |
| first_indexed | 2024-04-10T06:49:37Z |
| format | Article |
| id | doaj.art-8ebd080ce8a74151bccb59ad85e2ba92 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T06:49:37Z |
| publishDate | 2022-08-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-8ebd080ce8a74151bccb59ad85e2ba922023-02-28T08:50:45ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792022-08-01322111324Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in RatsBahador Hajimohammadi0Gilda Eslami1Hengameh Zandi2Saeedeh Sadat Hosseini3Mehrnoosh Shirdeli4Elahe Loni5Salman Ahmadian6Vahideh Askari7Maryam Sheykhzadegan8Raziyeh Barzegar-bafroui9Hossein Fallahzadeh10Mahmoud Vakili11 Associate Professor, Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Associate Professor, Department of Parasitology and Mycology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Associate Professor, Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran MSc in Medical Microbiology, Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran MSc in Food Hygiene and Safety, Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran MSc in Food Hygiene and Safety, Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran MSc in Parasitology, Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran MSc in Immunology, Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran MSc in Medical Microbiology, Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran MSc in Food Hygiene and Safety, Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Professor, Department of Biostatistics and Epidemiology, Faculty of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Associate Professor, Department of Community and Preventive Medicine, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Background and purpose: Transgenic rice is a type of rice that its genetic sequence has been changed to improve its quantity and quality. Bt (Bacillus thuringiensis) transgenic rice expresses Cry1Ab protein and is named Tarom Molaii. There are no studies on the effect of this type of transgenic rice on gastrointestinal health in Iran, so, this study investigated the effect of Tarom Molaii transgenic rice on common microbial flora of rat intestine. Materials and methods: In this experimental study, 24 Sprague Dawley (SD) rats received transgenic and non-transgenic rice in their diets for 90 days and were compared with the control group that received standard rat diet. The number of Escherichia coli, Bifidobacterium, Lactobacillus, and Enterococcus bacteria and the total number of aerobic and anaerobic bacteria in fecal samples were examined in jejunum, ileum, and duodenum samples on days 60, 90, and after killing the rats. Results: The study showed that except for the total number of anaerobic bacteria in the stool sample on day 90, there was no significant relationship between the study groups and the number of bacteria (P>0.05). There was an increase in the number of intestinal Lactobacillus in the transgenic rice-fed group and a decrease in the number of anaerobic bacteria in the transgenic rice-fed group compared with the control group and the non-transgenic rice-fed group. Conclusion: Consumption of transgenic rice in current study had no considerable effect on the number of common bacteria in the intestinal normal flora. But, long-term studies are needed in other laboratory animals.http://jmums.mazums.ac.ir/article-1-17619-en.htmltarom molaiitransgenic riceintestinal microbial floraanaerobic bacteriaaerobic bacteria |
| spellingShingle | Bahador Hajimohammadi Gilda Eslami Hengameh Zandi Saeedeh Sadat Hosseini Mehrnoosh Shirdeli Elahe Loni Salman Ahmadian Vahideh Askari Maryam Sheykhzadegan Raziyeh Barzegar-bafroui Hossein Fallahzadeh Mahmoud Vakili Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in Rats Journal of Mazandaran University of Medical Sciences tarom molaii transgenic rice intestinal microbial flora anaerobic bacteria aerobic bacteria |
| title | Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in Rats |
| title_full | Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in Rats |
| title_fullStr | Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in Rats |
| title_full_unstemmed | Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in Rats |
| title_short | Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in Rats |
| title_sort | effect of genetically modified rice on some intestinal microbial flora in rats |
| topic | tarom molaii transgenic rice intestinal microbial flora anaerobic bacteria aerobic bacteria |
| url | http://jmums.mazums.ac.ir/article-1-17619-en.html |
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