A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team
The advancement of the pediatric traumatic brain injury (TBI) knowledge base requires biospecimens and data from large samples. This study seeks to describe a novel clinical research modality to establish best practices for enrolling a diverse pediatric TBI population and quantifying key information...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-07-01
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| Series: | Brain Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3425/10/7/434 |
| _version_ | 1797563024276455424 |
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| author | Phoebe Lay Tapasvini Paralkar Syed Hadi Ahmed Minha Ghani Sara Muneer Ramsha Jinnah Carolyn Chen Jack Zeitz Alejandra Nitsch Nico Osier |
| author_facet | Phoebe Lay Tapasvini Paralkar Syed Hadi Ahmed Minha Ghani Sara Muneer Ramsha Jinnah Carolyn Chen Jack Zeitz Alejandra Nitsch Nico Osier |
| author_sort | Phoebe Lay |
| collection | DOAJ |
| description | The advancement of the pediatric traumatic brain injury (TBI) knowledge base requires biospecimens and data from large samples. This study seeks to describe a novel clinical research modality to establish best practices for enrolling a diverse pediatric TBI population and quantifying key information on enrollment into biobanks. Screening form responses were standardized and cleaned through Google Sheets. Data were used to analyze total individuals at each enrollment stage. R was utilized for final analysis, including logistic model and proportion statistical tests, to determine further significance and relationships. Issues throughout data cleaning shed light on limitations of the consent modality. The results suggest that through a diverse research team, the recruited sample exceeds traditional measures of representation (e.g., sex, race, ethnicity). Sex demographics of the study are representative of the local population. Screening for candidates is critical to the success of the consent modality. The consent modality may be modified to increase the diversity of the study population and accept bilingual candidates. Researchers must implement best practices, including increasing inclusivity of bilingual populations, utilizing technology, and improving participant follow-up, to improve health disparities for understudied clinical populations. |
| first_indexed | 2024-03-10T18:36:41Z |
| format | Article |
| id | doaj.art-8ebdc156a5a34d54bafb293e94acbbcc |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T18:36:41Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-8ebdc156a5a34d54bafb293e94acbbcc2023-11-20T06:11:03ZengMDPI AGBrain Sciences2076-34252020-07-0110743410.3390/brainsci10070434A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse TeamPhoebe Lay0Tapasvini Paralkar1Syed Hadi Ahmed2Minha Ghani3Sara Muneer4Ramsha Jinnah5Carolyn Chen6Jack Zeitz7Alejandra Nitsch8Nico Osier9College of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USACollege of Liberal Arts, The University of Texas at Austin, Austin, TX 78712, USAMcCombs School of Business, The University of Texas at Austin, Austin, TX 78712, USACollege of Liberal Arts, The University of Texas at Austin, Austin, TX 78712, USADell Medical School, The University of Texas at Austin, Austin, TX 78712, USAMcCombs School of Business, The University of Texas at Austin, Austin, TX 78712, USACollege of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USACollege of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USAMcCombs School of Business, The University of Texas at Austin, Austin, TX 78712, USADell Medical School, The University of Texas at Austin School of Nursing, Austin, TX 78712, USAThe advancement of the pediatric traumatic brain injury (TBI) knowledge base requires biospecimens and data from large samples. This study seeks to describe a novel clinical research modality to establish best practices for enrolling a diverse pediatric TBI population and quantifying key information on enrollment into biobanks. Screening form responses were standardized and cleaned through Google Sheets. Data were used to analyze total individuals at each enrollment stage. R was utilized for final analysis, including logistic model and proportion statistical tests, to determine further significance and relationships. Issues throughout data cleaning shed light on limitations of the consent modality. The results suggest that through a diverse research team, the recruited sample exceeds traditional measures of representation (e.g., sex, race, ethnicity). Sex demographics of the study are representative of the local population. Screening for candidates is critical to the success of the consent modality. The consent modality may be modified to increase the diversity of the study population and accept bilingual candidates. Researchers must implement best practices, including increasing inclusivity of bilingual populations, utilizing technology, and improving participant follow-up, to improve health disparities for understudied clinical populations.https://www.mdpi.com/2076-3425/10/7/434brain injuriestraumatic brain injurychildrendiversitystudent-ledparticipant-focused |
| spellingShingle | Phoebe Lay Tapasvini Paralkar Syed Hadi Ahmed Minha Ghani Sara Muneer Ramsha Jinnah Carolyn Chen Jack Zeitz Alejandra Nitsch Nico Osier A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team Brain Sciences brain injuries traumatic brain injury children diversity student-led participant-focused |
| title | A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team |
| title_full | A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team |
| title_fullStr | A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team |
| title_full_unstemmed | A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team |
| title_short | A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team |
| title_sort | novel clinical research modality for enrolling diverse participants using a diverse team |
| topic | brain injuries traumatic brain injury children diversity student-led participant-focused |
| url | https://www.mdpi.com/2076-3425/10/7/434 |
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