Spatial and temporal heterogeneity in the lineage progression of fine oligodendrocyte subtypes

Spatial and temporal heterogeneity in the lineage progression of fine oligodendrocyte subtypes

Abstract Background Oligodendrocytes are glial cells that support and insulate axons in the central nervous system through the production of myelin. Oligodendrocytes arise throughout embryonic and early postnatal development from oligodendrocyte precursor cells (OPCs), and recent work demonstrated t...

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Bibliographic Details
Main Authors: Markus M. Hilscher, Christoffer Mattsson Langseth, Petra Kukanja, Chika Yokota, Mats Nilsson, Gonçalo Castelo-Branco
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Biology
Subjects:
Oligodendrocytes
Lineage progression
Spatial transcriptomics
In situ sequencing
Cortex
Corpus callosum
Online Access:https://doi.org/10.1186/s12915-022-01325-z

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