The Influence of the Ketogenic Diet on the Immune Tolerant Microenvironment in Glioblastoma

The Influence of the Ketogenic Diet on the Immune Tolerant Microenvironment in Glioblastoma

Glioblastoma (GBM) represents an aggressive and immune-resistant cancer. Preclinical investigations have identified anti-tumor activity of a ketogenic diet (KD) potentially being used to target GBM’s glycolytic phenotype. Since immune cells in the microenvironment have a similar reliance upon nutrie...

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Bibliographic Details
Main Authors: Pravin Kesarwani, Shiva Kant, Yi Zhao, C. Ryan Miller, Prakash Chinnaiyan
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
ketogenic diet
GBM
immunosuppressive macrophages
CSF-1R inhibition
Online Access:https://www.mdpi.com/2072-6694/14/22/5550

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https://www.mdpi.com/2072-6694/14/22/5550

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