Parvovirus B19 infection during pregnancy

Parvovirus B19 (B19V) is a widespread pathogen causing infection that occurs mostly in children. Even though infection of B19V is mainly asymptomatic, it can bring about a few conditions that may require medical intervention, including erythema infectiosum (fifth disease), slapped cheek syndrome, pa...

Full description

Bibliographic Details
Main Authors: Pietruszka Katarzyna, Sliwinska Magdalena, Sikora Agnieszka
Format: Article
Language:English
Published: Sciendo 2022-07-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
Online Access:https://doi.org/10.2478/cipms-2022-0008
_version_ 1818502786589917184
author Pietruszka Katarzyna
Sliwinska Magdalena
Sikora Agnieszka
author_facet Pietruszka Katarzyna
Sliwinska Magdalena
Sikora Agnieszka
author_sort Pietruszka Katarzyna
collection DOAJ
description Parvovirus B19 (B19V) is a widespread pathogen causing infection that occurs mostly in children. Even though infection of B19V is mainly asymptomatic, it can bring about a few conditions that may require medical intervention, including erythema infectiosum (fifth disease), slapped cheek syndrome, papular-purpuric gloves and socks syndrome (PPGSS), as well as other disorders related to the hematological system. Despite the fact that the most common route of transmission is through the respiratory system, B19V can be also transmitted transplacentally from mother to foetus. Vertical transmission may lead to myocarditis, thrombocytopenia, neural manifestations, and foetal hydrops, which may be life-threatening conditions to both mother and foetus. Detection of B19V infection is based mostly on molecular and serological screening and it is performed after suspected exposure to pathogen or exhibition of symptoms. Currently, there is no specific medication against B19V infection, therefore, treatment is based on the elimination of symptoms. New therapies are, however, under development.
first_indexed 2024-12-10T21:15:05Z
format Article
id doaj.art-8ec0db24cc4c4169bbb92c80829b7983
institution Directory Open Access Journal
issn 2300-6676
language English
last_indexed 2024-12-10T21:15:05Z
publishDate 2022-07-01
publisher Sciendo
record_format Article
series Current Issues in Pharmacy and Medical Sciences
spelling doaj.art-8ec0db24cc4c4169bbb92c80829b79832022-12-22T01:33:20ZengSciendoCurrent Issues in Pharmacy and Medical Sciences2300-66762022-07-01351414610.2478/cipms-2022-0008Parvovirus B19 infection during pregnancyPietruszka Katarzyna0Sliwinska Magdalena1Sikora Agnieszka2Student Scientific Club, Department of Medical Microbiology, Medical University of Lublin, PolandIntercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, PolandDepartment of Medical Microbiology, Medical University of Lublin, PolandParvovirus B19 (B19V) is a widespread pathogen causing infection that occurs mostly in children. Even though infection of B19V is mainly asymptomatic, it can bring about a few conditions that may require medical intervention, including erythema infectiosum (fifth disease), slapped cheek syndrome, papular-purpuric gloves and socks syndrome (PPGSS), as well as other disorders related to the hematological system. Despite the fact that the most common route of transmission is through the respiratory system, B19V can be also transmitted transplacentally from mother to foetus. Vertical transmission may lead to myocarditis, thrombocytopenia, neural manifestations, and foetal hydrops, which may be life-threatening conditions to both mother and foetus. Detection of B19V infection is based mostly on molecular and serological screening and it is performed after suspected exposure to pathogen or exhibition of symptoms. Currently, there is no specific medication against B19V infection, therefore, treatment is based on the elimination of symptoms. New therapies are, however, under development.https://doi.org/10.2478/cipms-2022-0008parvovirus b19pregnancyfoetuscongenital infectionsnonimmune hydrops fetalisdiagnosis
spellingShingle Pietruszka Katarzyna
Sliwinska Magdalena
Sikora Agnieszka
Parvovirus B19 infection during pregnancy
Current Issues in Pharmacy and Medical Sciences
parvovirus b19
pregnancy
foetus
congenital infections
nonimmune hydrops fetalis
diagnosis
title Parvovirus B19 infection during pregnancy
title_full Parvovirus B19 infection during pregnancy
title_fullStr Parvovirus B19 infection during pregnancy
title_full_unstemmed Parvovirus B19 infection during pregnancy
title_short Parvovirus B19 infection during pregnancy
title_sort parvovirus b19 infection during pregnancy
topic parvovirus b19
pregnancy
foetus
congenital infections
nonimmune hydrops fetalis
diagnosis
url https://doi.org/10.2478/cipms-2022-0008
work_keys_str_mv AT pietruszkakatarzyna parvovirusb19infectionduringpregnancy
AT sliwinskamagdalena parvovirusb19infectionduringpregnancy
AT sikoraagnieszka parvovirusb19infectionduringpregnancy