A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility
Introduction: Several studies of neuropsychological measures have been undertaken in patients with psychotic disorders from low- and middle-income countries (LMICs). It is, however, unclear if the measures used in these studies are appropriate for cognitive screening in clinical settings. We underto...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | Schizophrenia Research: Cognition |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2215001320300081 |
| _version_ | 1818539044009672704 |
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| author | Emmanuel K. Mwesiga Dickens Akena Nastassja Koen Richard Senono Ekwaro A. Obuku Joy Louise Gumikiriza Reuben N. Robbins Noeline Nakasujja Dan J. Stein |
| author_facet | Emmanuel K. Mwesiga Dickens Akena Nastassja Koen Richard Senono Ekwaro A. Obuku Joy Louise Gumikiriza Reuben N. Robbins Noeline Nakasujja Dan J. Stein |
| author_sort | Emmanuel K. Mwesiga |
| collection | DOAJ |
| description | Introduction: Several studies of neuropsychological measures have been undertaken in patients with psychotic disorders from low- and middle-income countries (LMICs). It is, however, unclear if the measures used in these studies are appropriate for cognitive screening in clinical settings. We undertook a systematic review to determine if measures investigated in research on psychotic disorders in LMICs meet the clinical utility criteria proposed by The Working Group on Screening and Assessment. Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses were employed. We determined if tests had been validated against a comprehensive test battery, the duration and scope of the tests, the personnel administering the tests, and the means of administration. Results: A total of 31 articles were included in the review, of which 11 were from Africa. The studies included 3254 participants with psychosis and 1331 controls. 3 studies reported on the validation of the test against a comprehensive cognitive battery. Assessments took 1 h or less to administer in 6/31 studies. The average number of cognitive domains assessed was four. Nonspecialized staff were used in only 3/31 studies, and most studies used pen and paper tests (17/31). Conclusion: Neuropsychological measures used in research on psychotic disorders in LMICs typically do not meet the Working Group on Screening and Assessment clinical utility criteria for cognitive screening. Measures that have been validated in high-income countries but not in LMICs that do meet these criteria, such as the Brief Assessment of Cognition in Schizophrenia, therefore deserve further study in LMIC settings. |
| first_indexed | 2024-12-11T21:36:51Z |
| format | Article |
| id | doaj.art-8ec25212fae948c784af8e4b3d5399ec |
| institution | Directory Open Access Journal |
| issn | 2215-0013 |
| language | English |
| last_indexed | 2024-12-11T21:36:51Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Schizophrenia Research: Cognition |
| spelling | doaj.art-8ec25212fae948c784af8e4b3d5399ec2022-12-22T00:49:59ZengElsevierSchizophrenia Research: Cognition2215-00132020-12-0122100187A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utilityEmmanuel K. Mwesiga0Dickens Akena1Nastassja Koen2Richard Senono3Ekwaro A. Obuku4Joy Louise Gumikiriza5Reuben N. Robbins6Noeline Nakasujja7Dan J. Stein8Department of Psychiatry, Makerere University, Uganda; Department of Psychiatry and Neuroscience Institute, University of Cape Town, South Africa; Africa Centre for Systematic Reviews and Knowledge Translation, College of Health Sciences, Makerere University, Uganda; Corresponding author at: Department of Psychiatry and Mental Health, University of Cape Town, South Africa.Department of Psychiatry, Makerere University, Uganda; Africa Centre for Systematic Reviews and Knowledge Translation, College of Health Sciences, Makerere University, UgandaSA MRC Research Unit on Risk & Resilience in Mental Disorders, South Africa; Department of Psychiatry and Neuroscience Institute, University of Cape Town, South AfricaInfectious Disease Institute, Makerere University, UgandaAfrica Centre for Systematic Reviews and Knowledge Translation, College of Health Sciences, Makerere University, UgandaDepartment of Psychiatry, Makerere University, UgandaNew York State Psychiatric Institute, Columbia University Irving Medical Center, United States of AmericaDepartment of Psychiatry, Makerere University, UgandaDepartment of Psychiatry and Neuroscience Institute, University of Cape Town, South AfricaIntroduction: Several studies of neuropsychological measures have been undertaken in patients with psychotic disorders from low- and middle-income countries (LMICs). It is, however, unclear if the measures used in these studies are appropriate for cognitive screening in clinical settings. We undertook a systematic review to determine if measures investigated in research on psychotic disorders in LMICs meet the clinical utility criteria proposed by The Working Group on Screening and Assessment. Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses were employed. We determined if tests had been validated against a comprehensive test battery, the duration and scope of the tests, the personnel administering the tests, and the means of administration. Results: A total of 31 articles were included in the review, of which 11 were from Africa. The studies included 3254 participants with psychosis and 1331 controls. 3 studies reported on the validation of the test against a comprehensive cognitive battery. Assessments took 1 h or less to administer in 6/31 studies. The average number of cognitive domains assessed was four. Nonspecialized staff were used in only 3/31 studies, and most studies used pen and paper tests (17/31). Conclusion: Neuropsychological measures used in research on psychotic disorders in LMICs typically do not meet the Working Group on Screening and Assessment clinical utility criteria for cognitive screening. Measures that have been validated in high-income countries but not in LMICs that do meet these criteria, such as the Brief Assessment of Cognition in Schizophrenia, therefore deserve further study in LMIC settings.http://www.sciencedirect.com/science/article/pii/S2215001320300081CognitionPsychosisScreeningLow and middle-income countriesSystematic review |
| spellingShingle | Emmanuel K. Mwesiga Dickens Akena Nastassja Koen Richard Senono Ekwaro A. Obuku Joy Louise Gumikiriza Reuben N. Robbins Noeline Nakasujja Dan J. Stein A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility Schizophrenia Research: Cognition Cognition Psychosis Screening Low and middle-income countries Systematic review |
| title | A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility |
| title_full | A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility |
| title_fullStr | A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility |
| title_full_unstemmed | A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility |
| title_short | A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility |
| title_sort | systematic review of research on neuropsychological measures in psychotic disorders from low and middle income countries the question of clinical utility |
| topic | Cognition Psychosis Screening Low and middle-income countries Systematic review |
| url | http://www.sciencedirect.com/science/article/pii/S2215001320300081 |
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