<i>N</i>-[2-(4-Acetyl-1-Piperazinyl)Phenyl]-2-(3-Methylphenoxy)Acetamide (NAPMA) Inhibits Osteoclast Differentiation and Protects against Ovariectomy-Induced Osteoporosis

<i>N</i>-[2-(4-Acetyl-1-Piperazinyl)Phenyl]-2-(3-Methylphenoxy)Acetamide (NAPMA) Inhibits Osteoclast Differentiation and Protects against Ovariectomy-Induced Osteoporosis

Osteoclasts are large, multinucleated cells responsible for bone resorption and are induced in response to the regulatory activity of receptor activator of nuclear factor-kappa B ligand (RANKL). Excessive osteoclast activity causes pathological bone loss and destruction. Many studies have investigat...

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Bibliographic Details
Main Authors: Jinkyung Lee, Sun-Hee Ahn, Zhihao Chen, Sohi Kang, Dong Kyu Choi, Changjong Moon, Sang Hyun Min, Byung-Ju Park, Tae-Hoon Lee
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
NAPMA
osteoclast
ovariectomy
osteoporosis
bone loss
bone resorption
Online Access:https://www.mdpi.com/1420-3049/25/20/4855

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