Review on data analysis and application of high-throughput peptide arrays
This article introduces a high-throughput molecular screening chip： peptide arrays. As a kind of biochip， the peptide arrays are easy to synthesis， stable in probe chemistry， high-throughput in screening and highly specific compared with other biochips. To analyze the new high-throughput data， resea...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Shanghai Preventive Medicine Association
2023-01-01
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| Series: | Shanghai yufang yixue |
| Subjects: | |
| Online Access: | http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22753 |
| _version_ | 1797849648764813312 |
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| author | HUANG Junxiong TAO Yimin ZHONG Pei ZHAO Chunqing LI Xiaoguang WANG Hui |
| author_facet | HUANG Junxiong TAO Yimin ZHONG Pei ZHAO Chunqing LI Xiaoguang WANG Hui |
| author_sort | HUANG Junxiong |
| collection | DOAJ |
| description | This article introduces a high-throughput molecular screening chip： peptide arrays. As a kind of biochip， the peptide arrays are easy to synthesis， stable in probe chemistry， high-throughput in screening and highly specific compared with other biochips. To analyze the new high-throughput data， researchers have recently proposed a series of deep learning and bioinformatics methods to study the binding characteristics of peptide probes and target molecules. Those algorithms could be used to predict the binding affinity of protein targets against peptides. Moreover， peptide arrays could also play important roles in analyzing protein-protein interactions，screening novel drug peptides， disease diagnosis and general health assessment based on recent reports. The application of this new technology could provide novel insights into public health research. |
| first_indexed | 2024-04-09T18:48:11Z |
| format | Article |
| id | doaj.art-8ec4bbac3c9246a5b552e1e66987b28b |
| institution | Directory Open Access Journal |
| issn | 1004-9231 |
| language | zho |
| last_indexed | 2024-04-09T18:48:11Z |
| publishDate | 2023-01-01 |
| publisher | Shanghai Preventive Medicine Association |
| record_format | Article |
| series | Shanghai yufang yixue |
| spelling | doaj.art-8ec4bbac3c9246a5b552e1e66987b28b2023-04-10T09:29:39ZzhoShanghai Preventive Medicine AssociationShanghai yufang yixue1004-92312023-01-01351666910.19428/j.cnki.sjpm.2023.227531004-9231（2023）01-0066-04Review on data analysis and application of high-throughput peptide arraysHUANG Junxiong0TAO Yimin1ZHONG Pei2ZHAO Chunqing3LI Xiaoguang4WANG Hui5Shenzhen Digital Life Institute , Shenzhen Guangdong Province, Shanghai 518110, ChinaShenzhen Digital Life Institute , Shenzhen Guangdong Province, Shanghai 518110, ChinaShenzhen Digital Life Institute , Shenzhen Guangdong Province, Shanghai 518110, ChinaShenzhen Digital Life Institute , Shenzhen Guangdong Province, Shanghai 518110, ChinaSchool of Public Health , Shanghai Jiao Tong University, Shanghai 200025, ChinaSchool of Public Health , Shanghai Jiao Tong University, Shanghai 200025, ChinaThis article introduces a high-throughput molecular screening chip： peptide arrays. As a kind of biochip， the peptide arrays are easy to synthesis， stable in probe chemistry， high-throughput in screening and highly specific compared with other biochips. To analyze the new high-throughput data， researchers have recently proposed a series of deep learning and bioinformatics methods to study the binding characteristics of peptide probes and target molecules. Those algorithms could be used to predict the binding affinity of protein targets against peptides. Moreover， peptide arrays could also play important roles in analyzing protein-protein interactions，screening novel drug peptides， disease diagnosis and general health assessment based on recent reports. The application of this new technology could provide novel insights into public health research.http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22753peptide arraydeep learningppipublic health |
| spellingShingle | HUANG Junxiong TAO Yimin ZHONG Pei ZHAO Chunqing LI Xiaoguang WANG Hui Review on data analysis and application of high-throughput peptide arrays Shanghai yufang yixue peptide array deep learning ppi public health |
| title | Review on data analysis and application of high-throughput peptide arrays |
| title_full | Review on data analysis and application of high-throughput peptide arrays |
| title_fullStr | Review on data analysis and application of high-throughput peptide arrays |
| title_full_unstemmed | Review on data analysis and application of high-throughput peptide arrays |
| title_short | Review on data analysis and application of high-throughput peptide arrays |
| title_sort | review on data analysis and application of high throughput peptide arrays |
| topic | peptide array deep learning ppi public health |
| url | http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22753 |
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