Inhibiting NOXO1 and CYBA binding to reduce NADPH oxidase I dependent ROS damage in skin explants

Inhibiting NOXO1 and CYBA binding to reduce NADPH oxidase I dependent ROS damage in skin explants

NADPH oxidases (NOXs) are newly identified enzymes that generate intracellular reactive oxygen species (ROS) in skin cells. Recent studies demonstrated that NOX1 holoenzyme is expressed in human keratinocytes and melanocytes, which are implicated in skin photo-carcinogenesis due to the high amounts...

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Bibliographic Details
Main Authors: Prasadini Senevirathne, Alyssa Sterling, Mary Anne Refaei, Nazanin Mokhtarpour, Laura Gutierrez-Rivera, Joshua Garcia, Milena Dragovic, Gurdat Premnauth, Pearl Tsang, Ana Luisa Kadekaro, Edward J. Merino
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Reactive oxygen species
Apocynin
UV
Melanoma
Sunscreen
NOXO1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623004526

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http://www.sciencedirect.com/science/article/pii/S2211715623004526

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