Stem cells-derived exosomes alleviate neurodegeneration and Alzheimer’s pathogenesis by ameliorating neuroinflamation, and regulating the associated molecular pathways
Abstract Amyloid beta (Aβ) aggregation and tau hyper phosphorylation (p-tau) are key molecular factors in Alzheimer’s disease (AD). The abnormal formation and accumulation of Aβ and p-tau lead to the formation of amyloid plaques and neurofibrillary tangles (NFTs) which ultimately leads to neuroinfla...
Main Authors: | Muhammad Imran Khan, Eun Sun Jeong, Muhammad Zubair Khan, Jin Hyuk Shin, Jong Deog Kim |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-42485-4 |
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