In vitro inhibition of adhesion of Escherichia coli strains by Xylitol

The present study aimed to evaluate xylitol's antimicrobial and anti-adherence activities on Escherichia coli (ATCC 8739) and on another clinical strain enteropathogenic E. coli (EPEC). In vitro minimum inhibitory concentration (MIC) test and adhesion assays were performed using 0.5, 2.5 and 5....

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Bibliographic Details
Main Authors: Annelisa Farah da Silva, Érika Yoko Suzuki, Aline Siqueira Ferreira, Murilo Gomes Oliveira, Sílvio Silvério da Silva, Nádia Rezende Barbosa Raposo
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2011-04-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000200003
Description
Summary:The present study aimed to evaluate xylitol's antimicrobial and anti-adherence activities on Escherichia coli (ATCC 8739) and on another clinical strain enteropathogenic E. coli (EPEC). In vitro minimum inhibitory concentration (MIC) test and adhesion assays were performed using 0.5, 2.5 and 5.0% xylitol. It was found that xylitol did not have antimicrobial properties on these strains. The scanning electron microscopy (SEM) demonstrated that the slides treated with xylitol had a significant reduction in the number of bacilli and the inhibition of microbial adhesion was probably the xylitol's mechanism of action. Xylitol could be a possible alternative on the control of E. coli infections.
ISSN:1516-8913
1678-4324