Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital study

Purpose: This study aims to study the prevalence of DED and analyze risk factors in North Indian population. Methods: This was a cross-section hospital-based, observational study. Cases enrolled over 2 years (systematic random sampling) were administered ocular surface disease index questionnaire to...

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Main Authors: Jeewan Singh Titiyal, Ruchita Clara Falera, Manpreet Kaur, Vijay Sharma, Namrata Sharma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=2;spage=207;epage=211;aulast=Titiyal
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author Jeewan Singh Titiyal
Ruchita Clara Falera
Manpreet Kaur
Vijay Sharma
Namrata Sharma
author_facet Jeewan Singh Titiyal
Ruchita Clara Falera
Manpreet Kaur
Vijay Sharma
Namrata Sharma
author_sort Jeewan Singh Titiyal
collection DOAJ
description Purpose: This study aims to study the prevalence of DED and analyze risk factors in North Indian population. Methods: This was a cross-section hospital-based, observational study. Cases enrolled over 2 years (systematic random sampling) were administered ocular surface disease index questionnaire to evaluate the prevalence and risk factors of DED. Schirmer's test and tear break-up time were performed only in the subset of patients giving consent. Categorical data were assessed with Chi-square/Fisher's Exact test, and odds ratio was analyzed using bivariate and multivariate logistic regression. P < 0.05 was statistically significant. Results: A total of 15,625 patients were screened. The prevalence of DED was 32% (5000/15625); 9.9% (496/5000) had mild DED; 61.2% (3060/5000) had moderate DED; and 28.9% (1444/5000) had severe DED. Age group of 21–40 years, male sex, urban region, and desk job were associated with increased risk of DED. Hours of visual display terminal (VDT) usage significantly correlated with DED (P < 0.001), and 89.98% of patients with 4 h or more of VDT use had severe dry eye. Cigarette smoking and contact lens usage had increased odds of developing severe DED (P < 0.001). Objective tests were undertaken in 552 patients; of these, 81.3% (449/552) had severe DED. Conclusions: The prevalence of DED in North India is 32%, with the age group of 21–40 years affected most commonly. VDT use, smoking, and contact lens use were associated with increased odds of developing DED.
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spelling doaj.art-8ecc306d1a24403292aa44297b8d0a4b2022-12-22T00:33:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892018-01-0166220721110.4103/ijo.IJO_698_17Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital studyJeewan Singh TitiyalRuchita Clara FaleraManpreet KaurVijay SharmaNamrata SharmaPurpose: This study aims to study the prevalence of DED and analyze risk factors in North Indian population. Methods: This was a cross-section hospital-based, observational study. Cases enrolled over 2 years (systematic random sampling) were administered ocular surface disease index questionnaire to evaluate the prevalence and risk factors of DED. Schirmer's test and tear break-up time were performed only in the subset of patients giving consent. Categorical data were assessed with Chi-square/Fisher's Exact test, and odds ratio was analyzed using bivariate and multivariate logistic regression. P < 0.05 was statistically significant. Results: A total of 15,625 patients were screened. The prevalence of DED was 32% (5000/15625); 9.9% (496/5000) had mild DED; 61.2% (3060/5000) had moderate DED; and 28.9% (1444/5000) had severe DED. Age group of 21–40 years, male sex, urban region, and desk job were associated with increased risk of DED. Hours of visual display terminal (VDT) usage significantly correlated with DED (P < 0.001), and 89.98% of patients with 4 h or more of VDT use had severe dry eye. Cigarette smoking and contact lens usage had increased odds of developing severe DED (P < 0.001). Objective tests were undertaken in 552 patients; of these, 81.3% (449/552) had severe DED. Conclusions: The prevalence of DED in North India is 32%, with the age group of 21–40 years affected most commonly. VDT use, smoking, and contact lens use were associated with increased odds of developing DED.http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=2;spage=207;epage=211;aulast=TitiyalDry eye diseaseNorth Indiavisual display terminal
spellingShingle Jeewan Singh Titiyal
Ruchita Clara Falera
Manpreet Kaur
Vijay Sharma
Namrata Sharma
Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital study
Indian Journal of Ophthalmology
Dry eye disease
North India
visual display terminal
title Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital study
title_full Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital study
title_fullStr Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital study
title_full_unstemmed Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital study
title_short Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital study
title_sort prevalence and risk factors of dry eye disease in north india ocular surface disease index based cross sectional hospital study
topic Dry eye disease
North India
visual display terminal
url http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=2;spage=207;epage=211;aulast=Titiyal
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