Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus Treated with Double Filtration Plasmapheresis

Diffuse alveolar hemorrhage is a rare and life-threatening complication developed in systemic lupus erythematosus (SLE). We report a case of diffuse alveolar hemorrhage in a patient with lupus nephritis. The patient presented with acute respiratory and renal failure. Therefore, she was assessed as a...

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Main Authors: Güven ÇETİN, Tuba ÖZKAN, Seda TURGUT, Cumali KARATOPRAK, Rumeyza KAZANCIOĞLU
Format: Article
Language:English
Published: Galenos Publishing House 2018-07-01
Series:Bezmiâlem Science
Subjects:
Online Access: http://bezmialemscience.org/archives/archive-detail/article-preview/diffuse-alveolar-hemorrhage-in-systemic-lupus-eryt/20149
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author Güven ÇETİN
Tuba ÖZKAN
Seda TURGUT
Cumali KARATOPRAK
Rumeyza KAZANCIOĞLU
author_facet Güven ÇETİN
Tuba ÖZKAN
Seda TURGUT
Cumali KARATOPRAK
Rumeyza KAZANCIOĞLU
author_sort Güven ÇETİN
collection DOAJ
description Diffuse alveolar hemorrhage is a rare and life-threatening complication developed in systemic lupus erythematosus (SLE). We report a case of diffuse alveolar hemorrhage in a patient with lupus nephritis. The patient presented with acute respiratory and renal failure. Therefore, she was assessed as an activation of systemic lupus erythematosus. Despite pulse methylprednisolone, immunosuppressant drugs, and intravenous immunoglobulin (IVIG) therapy, the disease progressed. The patient participated in a plasmapheresis program, and double filtration plasmapheresis (DFPP) therapy was performed for six sessions in 6 days. Soon after the initiation of DFPP, she recovered with resolution of the radiological changes within 6 days and was successfully extubated. Thus, DFPP therapy should be considered for the treatment of diffuse alveolar hemorrhage, particularly in patients of systemic lupus erythematosus with lupus nephritis.
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spelling doaj.art-8ece30e171434955bb2d2206d158614d2023-02-15T16:20:34ZengGalenos Publishing HouseBezmiâlem Science2148-23732148-23732018-07-016322823210.14235/bs.2018.124713049054Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus Treated with Double Filtration PlasmapheresisGüven ÇETİN0Tuba ÖZKAN1Seda TURGUT2Cumali KARATOPRAK3Rumeyza KAZANCIOĞLU4 Department of Hematology, Bezmialem Vakif University School of Medicine, İstanbul, Turkey Department of Internal Diseases, Bezmialem Vakif University School of Medicine, İstanbul, Turkey Department of Internal Diseases, Bezmialem Vakif University School of Medicine, İstanbul, Turkey Department of Internal Diseases, Bezmialem Vakif University School of Medicine, İstanbul, Turkey Department of Nephrology, Bezmialem Vakif University School of Medicine, İstanbul, Turkey Diffuse alveolar hemorrhage is a rare and life-threatening complication developed in systemic lupus erythematosus (SLE). We report a case of diffuse alveolar hemorrhage in a patient with lupus nephritis. The patient presented with acute respiratory and renal failure. Therefore, she was assessed as an activation of systemic lupus erythematosus. Despite pulse methylprednisolone, immunosuppressant drugs, and intravenous immunoglobulin (IVIG) therapy, the disease progressed. The patient participated in a plasmapheresis program, and double filtration plasmapheresis (DFPP) therapy was performed for six sessions in 6 days. Soon after the initiation of DFPP, she recovered with resolution of the radiological changes within 6 days and was successfully extubated. Thus, DFPP therapy should be considered for the treatment of diffuse alveolar hemorrhage, particularly in patients of systemic lupus erythematosus with lupus nephritis. http://bezmialemscience.org/archives/archive-detail/article-preview/diffuse-alveolar-hemorrhage-in-systemic-lupus-eryt/20149 Diffuse alveolar hemorrhagesystemic lupus erythematosuslupus nephritisdouble filtration plasmapheresis
spellingShingle Güven ÇETİN
Tuba ÖZKAN
Seda TURGUT
Cumali KARATOPRAK
Rumeyza KAZANCIOĞLU
Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus Treated with Double Filtration Plasmapheresis
Bezmiâlem Science
Diffuse alveolar hemorrhage
systemic lupus erythematosus
lupus nephritis
double filtration plasmapheresis
title Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus Treated with Double Filtration Plasmapheresis
title_full Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus Treated with Double Filtration Plasmapheresis
title_fullStr Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus Treated with Double Filtration Plasmapheresis
title_full_unstemmed Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus Treated with Double Filtration Plasmapheresis
title_short Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus Treated with Double Filtration Plasmapheresis
title_sort diffuse alveolar hemorrhage in systemic lupus erythematosus treated with double filtration plasmapheresis
topic Diffuse alveolar hemorrhage
systemic lupus erythematosus
lupus nephritis
double filtration plasmapheresis
url http://bezmialemscience.org/archives/archive-detail/article-preview/diffuse-alveolar-hemorrhage-in-systemic-lupus-eryt/20149
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