Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report
OBJECTIVE: To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro. METHODS: Cross-sectional and retrospective study of thirty cases treated over a period of two decades. RESULTS: 17 men (56.7%) aged 14-67 years and 13 women aged 14-86 y...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier España
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| Series: | Clinics |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017000400218&lng=en&tlng=en |
| _version_ | 1818246239279382528 |
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| author | Maria de Fátima Borges Beatriz Hallal Jorge Lara Janaíne Machado Tomé Leopoldo Prezia de Araújo Flávio Cesar Lucas Bugiga Júlio Cláudio Sousa Jacqueline Mendes Fonseca Soares Roberto Alexandre Dezena Beatriz Pires Ferreira |
| author_facet | Maria de Fátima Borges Beatriz Hallal Jorge Lara Janaíne Machado Tomé Leopoldo Prezia de Araújo Flávio Cesar Lucas Bugiga Júlio Cláudio Sousa Jacqueline Mendes Fonseca Soares Roberto Alexandre Dezena Beatriz Pires Ferreira |
| author_sort | Maria de Fátima Borges |
| collection | DOAJ |
| description | OBJECTIVE: To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro. METHODS: Cross-sectional and retrospective study of thirty cases treated over a period of two decades. RESULTS: 17 men (56.7%) aged 14-67 years and 13 women aged 14-86 years were analyzed. Twenty-one patients underwent transphenoidal surgery, whichwas associated with somatostatin receptor ligands in 11 patients (39.3%), somatostatin receptor ligands + radiotherapyin 5 patients (17.8%), radiotherapy in 3 patients (10.7%), and radiotherapy + somatostatin receptorligands + cabergoline in 1 patient (3.6%). Additionally, 2 patients underwent radiotherapy and surgeryalone. Six patients received somatostatin receptor ligands before surgery, and 2 were not treated due to refusal and death. Nine patients have died, and 20 are being followed; 13 (65%) have growth hormonelevels o1 ng/mL, and 11 have normal insulin-like growth factor 1 levels. CONCLUSION: The current treatment options enable patients seen in regional reference centers to achieve strict control parameters, which allows them to be treated close to their homes. |
| first_indexed | 2024-12-12T14:45:39Z |
| format | Article |
| id | doaj.art-8ecf8496d90142b7903cad738dcbcc59 |
| institution | Directory Open Access Journal |
| issn | 1980-5322 |
| language | English |
| last_indexed | 2024-12-12T14:45:39Z |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-8ecf8496d90142b7903cad738dcbcc592022-12-22T00:21:07ZengElsevier EspañaClinics1980-532272421822310.6061/clinics/2017(04)05S1807-59322017000400218Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience ReportMaria de Fátima BorgesBeatriz Hallal Jorge LaraJanaíne Machado ToméLeopoldo Prezia de AraújoFlávio Cesar Lucas BugigaJúlio Cláudio SousaJacqueline Mendes Fonseca SoaresRoberto Alexandre DezenaBeatriz Pires FerreiraOBJECTIVE: To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro. METHODS: Cross-sectional and retrospective study of thirty cases treated over a period of two decades. RESULTS: 17 men (56.7%) aged 14-67 years and 13 women aged 14-86 years were analyzed. Twenty-one patients underwent transphenoidal surgery, whichwas associated with somatostatin receptor ligands in 11 patients (39.3%), somatostatin receptor ligands + radiotherapyin 5 patients (17.8%), radiotherapy in 3 patients (10.7%), and radiotherapy + somatostatin receptorligands + cabergoline in 1 patient (3.6%). Additionally, 2 patients underwent radiotherapy and surgeryalone. Six patients received somatostatin receptor ligands before surgery, and 2 were not treated due to refusal and death. Nine patients have died, and 20 are being followed; 13 (65%) have growth hormonelevels o1 ng/mL, and 11 have normal insulin-like growth factor 1 levels. CONCLUSION: The current treatment options enable patients seen in regional reference centers to achieve strict control parameters, which allows them to be treated close to their homes.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017000400218&lng=en&tlng=enAcromegalyGigantismTreatmentOutcome |
| spellingShingle | Maria de Fátima Borges Beatriz Hallal Jorge Lara Janaíne Machado Tomé Leopoldo Prezia de Araújo Flávio Cesar Lucas Bugiga Júlio Cláudio Sousa Jacqueline Mendes Fonseca Soares Roberto Alexandre Dezena Beatriz Pires Ferreira Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report Clinics Acromegaly Gigantism Treatment Outcome |
| title | Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report |
| title_full | Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report |
| title_fullStr | Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report |
| title_full_unstemmed | Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report |
| title_short | Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report |
| title_sort | treatment of acromegaly patients at the federal university of triangulo mineiro uftm experience report |
| topic | Acromegaly Gigantism Treatment Outcome |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017000400218&lng=en&tlng=en |
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