Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review
According to World Health Organization (WHO), fetal death is defined as the death of the fetus prior to its complete expulsion, independent of the duration of pregnancy, thus only ascribing the term stillbirth to fetal deaths in the case of pregnancies after 28 weeks of gestation. The great progress...
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| Format: | Article |
| Language: | English |
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Ion Motofei, Carol Davila University
2020-04-01
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| Series: | Journal of Mind and Medical Sciences |
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| Online Access: | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1234&context=jmms |
| _version_ | 1819064303146237952 |
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| author | Roxana Bohiltea Natalia Turcan Christina M. Cavinder Ionită Ducu Ioana Paunica Liliana Florina Andronache Monica Mihaela Cirstoiu |
| author_facet | Roxana Bohiltea Natalia Turcan Christina M. Cavinder Ionită Ducu Ioana Paunica Liliana Florina Andronache Monica Mihaela Cirstoiu |
| author_sort | Roxana Bohiltea |
| collection | DOAJ |
| description | According to World Health Organization (WHO), fetal death is defined as the death of the fetus prior to its complete expulsion, independent of the duration of pregnancy, thus only ascribing the term stillbirth to fetal deaths in the case of pregnancies after 28 weeks of gestation. The great progress of perinatology care is reflected in a significant reduction in the rate of stillbirths, especially in well-developed countries, with approximately 98% of stillbirth cases now occurring in poor and developing countries. Stillbirth powerfully impacts both the patient and the practitioner. Because nearly half of stillbirth cases result from apparently uncomplicated pregnancies, we considered it critical to review the known predictive markers for intrauterine fetal death. In both preterm and term infants, perinatal mortality is increased in fetuses small for their gestational age, and this risk grows proportionally with the severity of the fetal growth restriction. A protracted first stage of labor has not been associated with an increased risk of perinatal mortality and morbidity, but a prolonged second stage of labor has been associated with mortality and neonatal morbidity characterized by sepsis, seizures, and hypoxic-ischemic encephalopathy. Ultrasound examination of the placenta and the umbilical cord is essential for appropriate pregnancy monitoring. Various findings from ultrasound examination have been related to variable adverse perinatal outcomes, including intrauterine fetal death. After reviewing the evidence for predictors of intrauterine fetal death, we offer a general strategy for reducing the likelihood of stillbirths. |
| first_indexed | 2024-12-21T15:28:25Z |
| format | Article |
| id | doaj.art-8ecfbb70ba3a4f9a9f5aa538babfde5b |
| institution | Directory Open Access Journal |
| issn | 2392-7674 2392-7674 |
| language | English |
| last_indexed | 2024-12-21T15:28:25Z |
| publishDate | 2020-04-01 |
| publisher | Ion Motofei, Carol Davila University |
| record_format | Article |
| series | Journal of Mind and Medical Sciences |
| spelling | doaj.art-8ecfbb70ba3a4f9a9f5aa538babfde5b2022-12-21T18:58:51ZengIon Motofei, Carol Davila UniversityJournal of Mind and Medical Sciences2392-76742392-76742020-04-0171526010.22543/7674.71.P5260Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative reviewRoxana Bohiltea0Natalia Turcan1Christina M. Cavinder2Ionită Ducu3Ioana Paunica4Liliana Florina Andronache5Monica Mihaela Cirstoiu6CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIA CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIA VALPARAISO UNIVERSITY, COLLEGE OF NURSING AND HEALTH PROFESSIONS, VALPARAISO IN, USAUNIVERSITY EMERGENCY HOSPITAL BUCHAREST, DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, BUCHAREST, ROMANIATHE NATIONAL INSTITUTE OF DIABETES, NUTRITION AND METABOLIC DISEASES “PROF. N. C. PAULESCU”, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIA CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIA According to World Health Organization (WHO), fetal death is defined as the death of the fetus prior to its complete expulsion, independent of the duration of pregnancy, thus only ascribing the term stillbirth to fetal deaths in the case of pregnancies after 28 weeks of gestation. The great progress of perinatology care is reflected in a significant reduction in the rate of stillbirths, especially in well-developed countries, with approximately 98% of stillbirth cases now occurring in poor and developing countries. Stillbirth powerfully impacts both the patient and the practitioner. Because nearly half of stillbirth cases result from apparently uncomplicated pregnancies, we considered it critical to review the known predictive markers for intrauterine fetal death. In both preterm and term infants, perinatal mortality is increased in fetuses small for their gestational age, and this risk grows proportionally with the severity of the fetal growth restriction. A protracted first stage of labor has not been associated with an increased risk of perinatal mortality and morbidity, but a prolonged second stage of labor has been associated with mortality and neonatal morbidity characterized by sepsis, seizures, and hypoxic-ischemic encephalopathy. Ultrasound examination of the placenta and the umbilical cord is essential for appropriate pregnancy monitoring. Various findings from ultrasound examination have been related to variable adverse perinatal outcomes, including intrauterine fetal death. After reviewing the evidence for predictors of intrauterine fetal death, we offer a general strategy for reducing the likelihood of stillbirths.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1234&context=jmmsrisk factorspredictive markersprevention strategiesstillbirthfetal growth |
| spellingShingle | Roxana Bohiltea Natalia Turcan Christina M. Cavinder Ionită Ducu Ioana Paunica Liliana Florina Andronache Monica Mihaela Cirstoiu Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review Journal of Mind and Medical Sciences risk factors predictive markers prevention strategies stillbirth fetal growth |
| title | Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review |
| title_full | Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review |
| title_fullStr | Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review |
| title_full_unstemmed | Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review |
| title_short | Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review |
| title_sort | risk factors predictive markers and prevention strategies for intrauterine fetal death an integrative review |
| topic | risk factors predictive markers prevention strategies stillbirth fetal growth |
| url | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1234&context=jmms |
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