Hyperimmune Targeting Staphylococcal Toxins Effectively Protect Against USA 300 MRSA Infection in Mouse Bacteremia and Pneumonia Models

Hyperimmune Targeting Staphylococcal Toxins Effectively Protect Against USA 300 MRSA Infection in Mouse Bacteremia and Pneumonia Models

Staphylococcus aureus has been acquiring multiple drug resistance and has evolved into superbugs such as Methicillin/Vancomycin-resistant S. aureus (MRSA/VRSA) and, consequently, is a major cause of nosocomial and community infections associated with high morbidity and mortality for which no FDA-app...

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Bibliographic Details
Main Authors: Xiaobing Han, Roger Ortines, Ipsita Mukherjee, Tulasikumari Kanipakala, Thomas Kort, Shardulendra P. Sherchand, Grant Liao, Mark Mednikov, Agnes L. Chenine, M. Javad Aman, Cory L. Nykiforuk, Rajan P. Adhikari
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
S. aureus
hyperimmune
IBT-V02-F(ab’)2
bacteremia model
pneumonia model
IBT-V02 vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.893921/full

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