FPR2 participates in epithelial ovarian cancer (EOC) progression through RhoA-mediated M2 macrophage polarization

FPR2 participates in epithelial ovarian cancer (EOC) progression through RhoA-mediated M2 macrophage polarization

Abstract Background In our previous study, we found that formyl peptide receptor 2 (FPR2) promoted the invasion and metastasis of epithelial ovarian cancer (EOC) and could be a prognostic marker for EOC. In this study, we aimed to study the possible mechanism of FPR2 in promoting EOC progression. Me...

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Bibliographic Details
Main Authors: Xiaohui Xie, Juan He, Qiong Wang, Yaqiong Liu, Weiwei Chen, Kun Shi
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Ovarian Research
Subjects:
Epithelial ovarian cancer
FPR2
RhoA
Macrophage
Online Access:https://doi.org/10.1186/s13048-021-00932-8

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