Multi-perspective comparison of the immune microenvironment of primary colorectal cancer and liver metastases

Multi-perspective comparison of the immune microenvironment of primary colorectal cancer and liver metastases

Abstract Background Liver metastases are a major contributor to the poor immunotherapy response in colorectal cancer patients. However, the distinctions in the immune microenvironment between primary tumors and liver metastases are poorly characterized. The goal of this study was to compare the expr...

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Bibliographic Details
Main Authors: Yangsong He, Yanan Han, A-hui Fan, Danxiu Li, Boda Wang, Kun Ji, Xin Wang, Xiaodi Zhao, Yuanyuan Lu
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Translational Medicine
Subjects:
Colorectal cancer
Liver metastasis
Immune microenvironment
Immunosuppression
Comparison
Online Access:https://doi.org/10.1186/s12967-022-03667-2

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