A case of COVID-19-associated rhino-orbito-cerebral mucormycosis caused by Apophysomyces variabilis with a review of the literature
A fatal case of COVID-19-associated mucormycosis (CAM) affected a 40-year-old woman who was initially admitted to our hospital due to a SARS-CoV-2 infection. Her clinical condition worsened, and she finally died because of respiratory failure, hemodynamic instability, and mucormycosis with invasion...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2022.898477/full |
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| author | Mahzad Erami Mahzad Erami Hossein Mirhendi Hossein Mirhendi Mansooreh Momen-Heravi Seyed Jamal Hashemi Hezaveh Amir Hossein Ahsaniarani Seddighe Sadat Sabet Shima Aboutalebian Shima Aboutalebian |
| author_facet | Mahzad Erami Mahzad Erami Hossein Mirhendi Hossein Mirhendi Mansooreh Momen-Heravi Seyed Jamal Hashemi Hezaveh Amir Hossein Ahsaniarani Seddighe Sadat Sabet Shima Aboutalebian Shima Aboutalebian |
| author_sort | Mahzad Erami |
| collection | DOAJ |
| description | A fatal case of COVID-19-associated mucormycosis (CAM) affected a 40-year-old woman who was initially admitted to our hospital due to a SARS-CoV-2 infection. Her clinical condition worsened, and she finally died because of respiratory failure, hemodynamic instability, and mucormycosis with invasion into the orbit and probably the brain. According to DNA sequence analysis of the fungus isolated from the patient, Apophysomyces variabilis was involved. This is the first published case of CAM and the third case of mucormycosis due to this mold. |
| first_indexed | 2024-04-11T09:25:54Z |
| format | Article |
| id | doaj.art-8ed9034061e349f99f2fd860e94455c3 |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-04-11T09:25:54Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-8ed9034061e349f99f2fd860e94455c32022-12-22T04:32:02ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882022-10-011210.3389/fcimb.2022.898477898477A case of COVID-19-associated rhino-orbito-cerebral mucormycosis caused by Apophysomyces variabilis with a review of the literatureMahzad Erami0Mahzad Erami1Hossein Mirhendi2Hossein Mirhendi3Mansooreh Momen-Heravi4Seyed Jamal Hashemi Hezaveh5Amir Hossein Ahsaniarani6Seddighe Sadat Sabet7Shima Aboutalebian8Shima Aboutalebian9Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranInfectious Disease Research Center, Kashan University of Medical Sciences, Kashan, IranDepartment of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranMycology Reference Laboratory, Research Core Facilities Laboratory, Isfahan University of Medical Sciences, Isfahan, IranInfectious Disease Research Center, Kashan University of Medical Sciences, Kashan, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment Otorhinolaryngology, School of Medicine, Matini Hospital, Kashan University of Medical Sciences, Kashan, IranDepartment of Pharmaceutical, Kashan University of Medical Sciences, Kashan, IranDepartment of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranMycology Reference Laboratory, Research Core Facilities Laboratory, Isfahan University of Medical Sciences, Isfahan, IranA fatal case of COVID-19-associated mucormycosis (CAM) affected a 40-year-old woman who was initially admitted to our hospital due to a SARS-CoV-2 infection. Her clinical condition worsened, and she finally died because of respiratory failure, hemodynamic instability, and mucormycosis with invasion into the orbit and probably the brain. According to DNA sequence analysis of the fungus isolated from the patient, Apophysomyces variabilis was involved. This is the first published case of CAM and the third case of mucormycosis due to this mold.https://www.frontiersin.org/articles/10.3389/fcimb.2022.898477/fullmucormycosisapophysomyces variabilisCOVID-19immunocompetent patientinvasive fungal infectionantifungal susceptibility testing |
| spellingShingle | Mahzad Erami Mahzad Erami Hossein Mirhendi Hossein Mirhendi Mansooreh Momen-Heravi Seyed Jamal Hashemi Hezaveh Amir Hossein Ahsaniarani Seddighe Sadat Sabet Shima Aboutalebian Shima Aboutalebian A case of COVID-19-associated rhino-orbito-cerebral mucormycosis caused by Apophysomyces variabilis with a review of the literature Frontiers in Cellular and Infection Microbiology mucormycosis apophysomyces variabilis COVID-19 immunocompetent patient invasive fungal infection antifungal susceptibility testing |
| title | A case of COVID-19-associated rhino-orbito-cerebral mucormycosis caused by Apophysomyces variabilis with a review of the literature |
| title_full | A case of COVID-19-associated rhino-orbito-cerebral mucormycosis caused by Apophysomyces variabilis with a review of the literature |
| title_fullStr | A case of COVID-19-associated rhino-orbito-cerebral mucormycosis caused by Apophysomyces variabilis with a review of the literature |
| title_full_unstemmed | A case of COVID-19-associated rhino-orbito-cerebral mucormycosis caused by Apophysomyces variabilis with a review of the literature |
| title_short | A case of COVID-19-associated rhino-orbito-cerebral mucormycosis caused by Apophysomyces variabilis with a review of the literature |
| title_sort | case of covid 19 associated rhino orbito cerebral mucormycosis caused by apophysomyces variabilis with a review of the literature |
| topic | mucormycosis apophysomyces variabilis COVID-19 immunocompetent patient invasive fungal infection antifungal susceptibility testing |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2022.898477/full |
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