Amniotic fluid embolism: lessons for rapid recognition and intervention
Amniotic fluid embolism is a rare, often fatal complication of labor and delivery. The classic presentation is the sudden onset of a triad of clinical manifestations: hypoxia, hypotension and coagulopathy. Understanding of the syndrome as an immunologically mediated, complicated and often catastroph...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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University of São Paulo
2021-08-01
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| Series: | Autopsy and Case Reports |
| Subjects: | |
| Online Access: | https://www.revistas.usp.br/autopsy/article/view/190133 |
| _version_ | 1818788821064482816 |
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| author | Larry Nichols Rema Elmostafa Angela Nguyen Keisha R. Callins |
| author_facet | Larry Nichols Rema Elmostafa Angela Nguyen Keisha R. Callins |
| author_sort | Larry Nichols |
| collection | DOAJ |
| description | Amniotic fluid embolism is a rare, often fatal complication of labor and delivery. The classic presentation is the sudden onset of a triad of clinical manifestations: hypoxia, hypotension and coagulopathy. Understanding of the syndrome as an immunologically mediated, complicated and often catastrophic maternal response to fetal or placental antigens is coming into focus. New treatments such as extracorporeal membrane oxygenation (ECMO) and better use of old treatments such as transfusion offer hope, but the condition is often rapidly fatal, so saving the maternal and fetal lives depends on rapid recognition of the syndrome. This series of three cases illustrates the clinical features enabling the rapid recognition needed for successful treatment of amniotic fluid embolism syndrome. |
| first_indexed | 2024-12-18T14:29:45Z |
| format | Article |
| id | doaj.art-8edaa7896daa41639b693e83f8a22083 |
| institution | Directory Open Access Journal |
| issn | 2236-1960 |
| language | English |
| last_indexed | 2024-12-18T14:29:45Z |
| publishDate | 2021-08-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Autopsy and Case Reports |
| spelling | doaj.art-8edaa7896daa41639b693e83f8a220832022-12-21T21:04:37ZengUniversity of São PauloAutopsy and Case Reports2236-19602021-08-0111Amniotic fluid embolism: lessons for rapid recognition and interventionLarry Nichols0Rema Elmostafa1 Angela Nguyen2 Keisha R. Callins3Mercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USA Mercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USA Mercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USA Mercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USAAmniotic fluid embolism is a rare, often fatal complication of labor and delivery. The classic presentation is the sudden onset of a triad of clinical manifestations: hypoxia, hypotension and coagulopathy. Understanding of the syndrome as an immunologically mediated, complicated and often catastrophic maternal response to fetal or placental antigens is coming into focus. New treatments such as extracorporeal membrane oxygenation (ECMO) and better use of old treatments such as transfusion offer hope, but the condition is often rapidly fatal, so saving the maternal and fetal lives depends on rapid recognition of the syndrome. This series of three cases illustrates the clinical features enabling the rapid recognition needed for successful treatment of amniotic fluid embolism syndrome.https://www.revistas.usp.br/autopsy/article/view/190133Amniotic fluid embolismMaternal mortalityAutopsyExtracorporeal membrane oxygenation |
| spellingShingle | Larry Nichols Rema Elmostafa Angela Nguyen Keisha R. Callins Amniotic fluid embolism: lessons for rapid recognition and intervention Autopsy and Case Reports Amniotic fluid embolism Maternal mortality Autopsy Extracorporeal membrane oxygenation |
| title | Amniotic fluid embolism: lessons for rapid recognition and intervention |
| title_full | Amniotic fluid embolism: lessons for rapid recognition and intervention |
| title_fullStr | Amniotic fluid embolism: lessons for rapid recognition and intervention |
| title_full_unstemmed | Amniotic fluid embolism: lessons for rapid recognition and intervention |
| title_short | Amniotic fluid embolism: lessons for rapid recognition and intervention |
| title_sort | amniotic fluid embolism lessons for rapid recognition and intervention |
| topic | Amniotic fluid embolism Maternal mortality Autopsy Extracorporeal membrane oxygenation |
| url | https://www.revistas.usp.br/autopsy/article/view/190133 |
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