Prediction of protein structural class with Rough Sets
<p>Abstract</p> <p>Background</p> <p>A new method for the prediction of protein structural classes is constructed based on Rough Sets algorithm, which is a rule-based data mining method. Amino acid compositions and 8 physicochemical properties data are used as condition...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-01-01
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| Series: | BMC Bioinformatics |
| Online Access: | http://www.biomedcentral.com/1471-2105/7/20 |
| _version_ | 1818859343815114752 |
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| author | Wang Jiang Qin Jie Zhang Lida Liu Shi Cao Youfang Tang Kexuan |
| author_facet | Wang Jiang Qin Jie Zhang Lida Liu Shi Cao Youfang Tang Kexuan |
| author_sort | Wang Jiang |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>A new method for the prediction of protein structural classes is constructed based on Rough Sets algorithm, which is a rule-based data mining method. Amino acid compositions and 8 physicochemical properties data are used as conditional attributes for the construction of decision system. After reducing the decision system, decision rules are generated, which can be used to classify new objects.</p> <p>Results</p> <p>In this study, self-consistency and jackknife tests on the datasets constructed by G.P. Zhou (Journal of Protein Chemistry, 1998, 17: 729–738) are used to verify the performance of this method, and are compared with some of prior works. The results showed that the rough sets approach is very promising and may play a complementary role to the existing powerful approaches, such as the component-coupled, neural network, SVM, and LogitBoost approaches.</p> <p>Conclusion</p> <p>The results with high success rates indicate that the rough sets approach as proposed in this paper might hold a high potential to become a useful tool in bioinformatics.</p> |
| first_indexed | 2024-12-19T09:10:41Z |
| format | Article |
| id | doaj.art-8edcb84018d64c8d9f781fd2406c7848 |
| institution | Directory Open Access Journal |
| issn | 1471-2105 |
| language | English |
| last_indexed | 2024-12-19T09:10:41Z |
| publishDate | 2006-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Bioinformatics |
| spelling | doaj.art-8edcb84018d64c8d9f781fd2406c78482022-12-21T20:28:12ZengBMCBMC Bioinformatics1471-21052006-01-01712010.1186/1471-2105-7-20Prediction of protein structural class with Rough SetsWang JiangQin JieZhang LidaLiu ShiCao YoufangTang Kexuan<p>Abstract</p> <p>Background</p> <p>A new method for the prediction of protein structural classes is constructed based on Rough Sets algorithm, which is a rule-based data mining method. Amino acid compositions and 8 physicochemical properties data are used as conditional attributes for the construction of decision system. After reducing the decision system, decision rules are generated, which can be used to classify new objects.</p> <p>Results</p> <p>In this study, self-consistency and jackknife tests on the datasets constructed by G.P. Zhou (Journal of Protein Chemistry, 1998, 17: 729–738) are used to verify the performance of this method, and are compared with some of prior works. The results showed that the rough sets approach is very promising and may play a complementary role to the existing powerful approaches, such as the component-coupled, neural network, SVM, and LogitBoost approaches.</p> <p>Conclusion</p> <p>The results with high success rates indicate that the rough sets approach as proposed in this paper might hold a high potential to become a useful tool in bioinformatics.</p>http://www.biomedcentral.com/1471-2105/7/20 |
| spellingShingle | Wang Jiang Qin Jie Zhang Lida Liu Shi Cao Youfang Tang Kexuan Prediction of protein structural class with Rough Sets BMC Bioinformatics |
| title | Prediction of protein structural class with Rough Sets |
| title_full | Prediction of protein structural class with Rough Sets |
| title_fullStr | Prediction of protein structural class with Rough Sets |
| title_full_unstemmed | Prediction of protein structural class with Rough Sets |
| title_short | Prediction of protein structural class with Rough Sets |
| title_sort | prediction of protein structural class with rough sets |
| url | http://www.biomedcentral.com/1471-2105/7/20 |
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