Comparison of the short-term efficacy of different Amplatzer models and similar occluders in the treatment of patent foramen ovale
ObjectiveTo compare the recent efficacy and safety of different Amplatzer models and similar occluder in the treatment of patent foramen ovale (PFO).MethodsPatients with PFO complicated with cryptogenic stroke or migraine who underwent transcatheter closure of PFO in the First Affiliated Hospital of...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1092465/full |
| _version_ | 1797783248687857664 |
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| author | Yuxuan Lou Yuxuan Lou Yang Hua Jing Shi Fengze Yang Yifei Wang Yang Yang Wei Sun Xiangqing Kong Xiangqing Kong Hao Zhang |
| author_facet | Yuxuan Lou Yuxuan Lou Yang Hua Jing Shi Fengze Yang Yifei Wang Yang Yang Wei Sun Xiangqing Kong Xiangqing Kong Hao Zhang |
| author_sort | Yuxuan Lou |
| collection | DOAJ |
| description | ObjectiveTo compare the recent efficacy and safety of different Amplatzer models and similar occluder in the treatment of patent foramen ovale (PFO).MethodsPatients with PFO complicated with cryptogenic stroke or migraine who underwent transcatheter closure of PFO in the First Affiliated Hospital of Nanjing Medical University from September 2019 to March 2021 were selected. Patients were grouped according to the type of occluder device. The basic data of the patients were collected and followed up within 1 year after occlusion. Effectiveness was defined as no recurrence of stroke/remission of migraine symptoms and a negative postoperative foaming test, and safety events were counted as the combined results of serious adverse events.ResultsA total of 92 patients were selected, including 45 cases in the symmetrical group and 47 cases in the asymmetric group. There were no serious adverse events in the 2 groups during follow-up. 3 days and 1 month after occlusion, the number of shunt patients in the asymmetric group was significantly less than that in the symmetric group (χ2 = 5.484, P = 0.019; χ2 = 5.146, P = 0.023). The negative rate of blocked residual shunts in the asymmetric group was higher than that in the symmetric group at 1, 3, 6 and 12 months after occlusion (χ2 = 6.473, P = 0.011; χ2 = 4.305, P = 0.038; χ2 = 4.842, P = 0.027; χ2 = 4.034, P = 0.045). Headache in migraine patients in the asymmetric group was significantly better than headache in patients in the symmetric group (P = 0.038; P = 0.049).ConclusionAsymmetric Amplatzer and similar occluders provide greater efficacy in short-term occlusion than symmetric ones. |
| first_indexed | 2024-03-13T00:23:22Z |
| format | Article |
| id | doaj.art-8edf55019ef94787856bd8cb8e084da5 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-03-13T00:23:22Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-8edf55019ef94787856bd8cb8e084da52023-07-11T11:35:03ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-07-011010.3389/fcvm.2023.10924651092465Comparison of the short-term efficacy of different Amplatzer models and similar occluders in the treatment of patent foramen ovaleYuxuan Lou0Yuxuan Lou1Yang Hua2Jing Shi3Fengze Yang4Yifei Wang5Yang Yang6Wei Sun7Xiangqing Kong8Xiangqing Kong9Hao Zhang10Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaSoutheast University School of Medicine, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaSoutheast University School of Medicine, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaObjectiveTo compare the recent efficacy and safety of different Amplatzer models and similar occluder in the treatment of patent foramen ovale (PFO).MethodsPatients with PFO complicated with cryptogenic stroke or migraine who underwent transcatheter closure of PFO in the First Affiliated Hospital of Nanjing Medical University from September 2019 to March 2021 were selected. Patients were grouped according to the type of occluder device. The basic data of the patients were collected and followed up within 1 year after occlusion. Effectiveness was defined as no recurrence of stroke/remission of migraine symptoms and a negative postoperative foaming test, and safety events were counted as the combined results of serious adverse events.ResultsA total of 92 patients were selected, including 45 cases in the symmetrical group and 47 cases in the asymmetric group. There were no serious adverse events in the 2 groups during follow-up. 3 days and 1 month after occlusion, the number of shunt patients in the asymmetric group was significantly less than that in the symmetric group (χ2 = 5.484, P = 0.019; χ2 = 5.146, P = 0.023). The negative rate of blocked residual shunts in the asymmetric group was higher than that in the symmetric group at 1, 3, 6 and 12 months after occlusion (χ2 = 6.473, P = 0.011; χ2 = 4.305, P = 0.038; χ2 = 4.842, P = 0.027; χ2 = 4.034, P = 0.045). Headache in migraine patients in the asymmetric group was significantly better than headache in patients in the symmetric group (P = 0.038; P = 0.049).ConclusionAsymmetric Amplatzer and similar occluders provide greater efficacy in short-term occlusion than symmetric ones.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1092465/fullpatent foramen ovalecryptogenic strokemigraineclosureAmplatzer occluder |
| spellingShingle | Yuxuan Lou Yuxuan Lou Yang Hua Jing Shi Fengze Yang Yifei Wang Yang Yang Wei Sun Xiangqing Kong Xiangqing Kong Hao Zhang Comparison of the short-term efficacy of different Amplatzer models and similar occluders in the treatment of patent foramen ovale Frontiers in Cardiovascular Medicine patent foramen ovale cryptogenic stroke migraine closure Amplatzer occluder |
| title | Comparison of the short-term efficacy of different Amplatzer models and similar occluders in the treatment of patent foramen ovale |
| title_full | Comparison of the short-term efficacy of different Amplatzer models and similar occluders in the treatment of patent foramen ovale |
| title_fullStr | Comparison of the short-term efficacy of different Amplatzer models and similar occluders in the treatment of patent foramen ovale |
| title_full_unstemmed | Comparison of the short-term efficacy of different Amplatzer models and similar occluders in the treatment of patent foramen ovale |
| title_short | Comparison of the short-term efficacy of different Amplatzer models and similar occluders in the treatment of patent foramen ovale |
| title_sort | comparison of the short term efficacy of different amplatzer models and similar occluders in the treatment of patent foramen ovale |
| topic | patent foramen ovale cryptogenic stroke migraine closure Amplatzer occluder |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1092465/full |
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