Comprehensive Analysis of DNA Methyltransferases Expression in Primary and Relapsed Ovarian Carcinoma

Comprehensive Analysis of DNA Methyltransferases Expression in Primary and Relapsed Ovarian Carcinoma

Background: Despite recent advances in epithelial ovarian carcinoma (EOC) treatment, its recurrence and mortality rates have not improved significantly. DNA hypermethylation has generally been associated with an ominous prognosis and chemotherapy resistance, but the role of DNA methyltransferases (D...

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Bibliographic Details
Main Authors: Efthymia Papakonstantinou, Ioanna Pappa, Georgios Androutsopoulos, Georgios Adonakis, Ioannis Maroulis, Vasiliki Tzelepi
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
DNA methylation
DNA methyltransferases
DNMT
ovarian cancer
high-grade ovarian cancer
relapsed ovarian cancer
Online Access:https://www.mdpi.com/2072-6694/15/20/4950

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