Phosphomannosylation and the Functional Analysis of the Extended Candida albicans MNN4-Like Gene Family

Phosphomannosylation and the Functional Analysis of the Extended Candida albicans MNN4-Like Gene Family

Phosphomannosylation is a modification of cell wall proteins that occurs in some species of yeast-like organisms, including the human pathogen Candida albicans. These modified mannans confer a negative charge to the wall, which is important for the interactions with phagocytic cells of the immune sy...

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Bibliographic Details
Main Authors: Roberto J. González-Hernández, Kai Jin, Marco J. Hernández-Chávez, Diana F. Díaz-Jiménez, Elías Trujillo-Esquivel, Diana M. Clavijo-Giraldo, Alma K. Tamez-Castrellón, Bernardo Franco, Neil A. R. Gow, Héctor M. Mora-Montes
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
cell wall
phosphomannosylation
Candida albicans
phagocytosis
phosphomannosyltransferase
CRISPR-Cas9 system
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02156/full

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