Modulating Nucleation by Kosmotropes and Chaotropes: Testing the Waters
Water is a fundamental solvent sustaining life, key to the conformations and equilibria associated with solute species. Emerging studies on nucleation and crystallization phenomena reveal that the dynamics of hydration associated with mineral precursors are critical in determining material formation...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-10-01
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| Series: | Crystals |
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| Online Access: | https://www.mdpi.com/2073-4352/7/10/302 |
| _version_ | 1811187662788231168 |
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| author | Ashit Rao Denis Gebauer Helmut Cölfen |
| author_facet | Ashit Rao Denis Gebauer Helmut Cölfen |
| author_sort | Ashit Rao |
| collection | DOAJ |
| description | Water is a fundamental solvent sustaining life, key to the conformations and equilibria associated with solute species. Emerging studies on nucleation and crystallization phenomena reveal that the dynamics of hydration associated with mineral precursors are critical in determining material formation and growth. With certain small molecules affecting the hydration and conformational stability of co-solutes, this study systematically explores the effects of these chaotropes and kosmotropes as well as certain sugar enantiomers on the early stages of calcium carbonate formation. These small molecules appear to modulate mineral nucleation in a class-dependent manner. The observed effects are finite in comparison to the established, strong interactions between charged polymers and intermediate mineral forms. Thus, perturbations to hydration dynamics of ion clusters by co-solute species can affect nucleation phenomena in a discernable manner. |
| first_indexed | 2024-04-11T14:07:09Z |
| format | Article |
| id | doaj.art-8eeea40f15494e02b4a4b31103dcb161 |
| institution | Directory Open Access Journal |
| issn | 2073-4352 |
| language | English |
| last_indexed | 2024-04-11T14:07:09Z |
| publishDate | 2017-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Crystals |
| spelling | doaj.art-8eeea40f15494e02b4a4b31103dcb1612022-12-22T04:19:52ZengMDPI AGCrystals2073-43522017-10-0171030210.3390/cryst7100302cryst7100302Modulating Nucleation by Kosmotropes and Chaotropes: Testing the WatersAshit Rao0Denis Gebauer1Helmut Cölfen2Department of Chemistry, Universitätsstr. 10, University of Konstanz, Konstanz 78464, GermanyDepartment of Chemistry, Universitätsstr. 10, University of Konstanz, Konstanz 78464, GermanyDepartment of Chemistry, Universitätsstr. 10, University of Konstanz, Konstanz 78464, GermanyWater is a fundamental solvent sustaining life, key to the conformations and equilibria associated with solute species. Emerging studies on nucleation and crystallization phenomena reveal that the dynamics of hydration associated with mineral precursors are critical in determining material formation and growth. With certain small molecules affecting the hydration and conformational stability of co-solutes, this study systematically explores the effects of these chaotropes and kosmotropes as well as certain sugar enantiomers on the early stages of calcium carbonate formation. These small molecules appear to modulate mineral nucleation in a class-dependent manner. The observed effects are finite in comparison to the established, strong interactions between charged polymers and intermediate mineral forms. Thus, perturbations to hydration dynamics of ion clusters by co-solute species can affect nucleation phenomena in a discernable manner.https://www.mdpi.com/2073-4352/7/10/302crystallizationnucleationkosmotropeschaotropessmall moleculeshydration |
| spellingShingle | Ashit Rao Denis Gebauer Helmut Cölfen Modulating Nucleation by Kosmotropes and Chaotropes: Testing the Waters Crystals crystallization nucleation kosmotropes chaotropes small molecules hydration |
| title | Modulating Nucleation by Kosmotropes and Chaotropes: Testing the Waters |
| title_full | Modulating Nucleation by Kosmotropes and Chaotropes: Testing the Waters |
| title_fullStr | Modulating Nucleation by Kosmotropes and Chaotropes: Testing the Waters |
| title_full_unstemmed | Modulating Nucleation by Kosmotropes and Chaotropes: Testing the Waters |
| title_short | Modulating Nucleation by Kosmotropes and Chaotropes: Testing the Waters |
| title_sort | modulating nucleation by kosmotropes and chaotropes testing the waters |
| topic | crystallization nucleation kosmotropes chaotropes small molecules hydration |
| url | https://www.mdpi.com/2073-4352/7/10/302 |
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